{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:27:16Z","timestamp":1789194436510,"version":"build-2803163510"},"reference-count":19,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>\n                      This study aimed to investigate the outcomes of permanent Iodine-125 (\n                      <jats:sup>125<\/jats:sup>\n                      I) radiotherapy for patients with unresectable retroperitoneal malignant tumor.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Twenty-six patients with retroperitoneal malignant tumors were implanted with\n                      <jats:sup>125<\/jats:sup>\n                      I seeds under ultrasound guidance from June 2012 to June 2015. The patients were then followed up for 3 to 36 months after the implantation. During the follow-up, pain relief, control of tumor growth, over survival rate, and complications were evaluated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Most of the patients (90%, 24\/26) suffered from mild to severe pain before\n                      <jats:sup>125<\/jats:sup>\n                      I seed treatment. After 1-month treatment, 16 patients had 100% pain relief, 4 patients had at least 50% pain relief, and 4 patients had no response, showing 83.3% of pain relief response. Results of computed tomography scan after 2-month\n                      <jats:sup>125<\/jats:sup>\n                      I treatment indicated that 3 patients had complete remission in the tumor size, 20 patients had partial remission in tumor size, 2 patients were stable, and 1 patient had progressive disease, accounting for 88.4% response in tumor size remission. The median survival of the 26 patients was 11 months. The 1-year and 2-year overall survival rates were 46% and 27%, respectively. The median survival of the 5 patients with pancreatic cancer was 9.4 months. None of the patients had any severe complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      <jats:sup>125<\/jats:sup>\n                      I implantation could effectively relieve the pain in the patients with advanced primary or metastatic retroperitoneal malignant tumors and suppress local tumor progress.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1533033819825845","type":"journal-article","created":{"date-parts":[[2019,1,31]],"date-time":"2019-01-31T23:40:42Z","timestamp":1548978042000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Permanent Iodine-125 Seed Implantation for the Treatment of Nonresectable Retroperitoneal Malignant Tumors"],"prefix":"10.1177","volume":"18","author":[{"given":"Qingchun","family":"Li","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Tian","sequence":"additional","affiliation":[{"name":"Center of Physical Examination, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongyan","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Liang","sequence":"additional","affiliation":[{"name":"Center of Physical Examination, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianbin","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1842-3752","authenticated-orcid":false,"given":"Baodong","family":"Gai","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,1,31]]},"reference":[{"key":"bibr1-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1007\/s13193-015-0404-1"},{"key":"bibr2-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1186\/1748-717X-6-138"},{"key":"bibr3-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-009-1703-0"},{"key":"bibr4-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2011.03.006"},{"key":"bibr5-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2007.12.016"},{"key":"bibr6-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810101)47:1<207::AID-CNCR2820470134>3.0.CO;2-6"},{"key":"bibr7-1533033819825845","doi-asserted-by":"publisher","DOI":"10.5694\/mja11.10890"},{"issue":"2","key":"bibr8-1533033819825845","first-page":"e9","volume":"51","author":"Jiang G","year":"2015","journal-title":"Indian J Cancer"},{"key":"bibr9-1533033819825845","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.20.9009"},{"key":"bibr10-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2012.05.007"},{"key":"bibr11-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1177\/030089160509100410"},{"key":"bibr12-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2011.03.043"},{"key":"bibr13-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2388(199711\/12)13:6<431::AID-SSU7>3.0.CO;2-B"},{"key":"bibr14-1533033819825845","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i38.6479"},{"issue":"20","key":"bibr15-1533033819825845","first-page":"3034","volume":"18","author":"Ni RH","year":"2014","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"bibr16-1533033819825845","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2013.171"},{"key":"bibr17-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2015.07.011"},{"key":"bibr18-1533033819825845","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-016-0761-2"},{"key":"bibr19-1533033819825845","author":"\u201cPancreatic Cancer Treatment (PDQ\u00ae) Health Professional Version\u201d","journal-title":"Updated February 21, 2014"}],"container-title":["Technology in Cancer Research &amp; 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