{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:29:34Z","timestamp":1777940974372,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010014","name":"Six Talent Peaks Project in Jiangsu Province","doi-asserted-by":"publisher","award":["WSN-119"],"award-info":[{"award-number":["WSN-119"]}],"id":[{"id":"10.13039\/501100010014","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Cervical lymph nodes metastases are one of the most significant prognostic factors in patients with laryngeal carcinoma, whether treatment by surgery or by radiotherapy. The current study retrospected the postoperative radiotherapy of locally advanced supraglottic and glottic laryngeal carcinoma (at a greater risk of lymph node metastasis) to determine the effect of radiotherapy excluding cervical level \u2163 lymph nodes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients of supraglottic type and glottic type were irradiated with level \u2163 from January 2012 to June 2013, without level \u2163 from July 2013 to December 2014, according to physicians\u2019 decision. Ninety-three patients were selective neck irradiation (SNI) of levels \u2161-\u2163 (Group A) and 87 patients were SNI of levels \u2161 and \u2162 (Group B). The comparison between Group A and Group B was made with observation of clinical risk of recurrence and radiation complications, as well as overall survival (OS), progress-free survival (PFS) and regional nodal recurrence-free survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>No remarkable difference was observed in the distribution of recurrence, levels of relapse, OS, PFS and regional nodal recurrence-free survival between the 2 groups (p &gt; 0.05). Mean radiation dose at level \u2163, thyroid and cervical esophagus showed significant difference between the 2 therapeutic groups (p &lt; 0.01). As regard radiation complications, no significant difference was found in radiation dermatitis of any grade between the 2 groups (p &gt; 0.05). However, there was remarkable difference in clinical hypothyroidism and radiation esophagitis between Group A and Group B (p &lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Radiotherapy after surgery omitting level \u2163 may improve the quality of life in patients with locally advanced supraglottic and glottic laryngeal carcinoma, won\u2019t worsen the prognosis as well.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1533033820985876","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T05:03:09Z","timestamp":1612155789000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Postoperative Radiotherapy Omitting Level \u2163 for Locally Advanced Supraglottic and Glottic Laryngeal Carcinoma"],"prefix":"10.1177","volume":"20","author":[{"given":"Yang","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Xuzhou Medical University Affiliated Hospital, Xuzhou, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longzhen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Xuzhou Medical University Affiliated Hospital, Xuzhou, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianyou","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Xuzhou Medical University Affiliated Hospital, Xuzhou, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liantao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Xuzhou Medical University Affiliated Hospital, Xuzhou, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Xuzhou Medical University Affiliated Hospital, Xuzhou, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5667-2891","authenticated-orcid":false,"given":"Hongmin","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Public Health, Xuzhou Medical University, Xuzhou, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,2,1]]},"reference":[{"key":"bibr1-1533033820985876","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2014.1671"},{"issue":"10","key":"bibr2-1533033820985876","first-page":"1138","volume":"26","author":"Zhang Q","year":"2007","journal-title":"Ai 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