{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:07:09Z","timestamp":1787774829514,"version":"build-2784847793"},"reference-count":53,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"the Guangdong Basic and Applied Basic Research Foundation","award":["2018A030307079"],"award-info":[{"award-number":["2018A030307079"]}]},{"name":"the Guangdong Basic and Applied Basic Research Foundation","award":["2019A1515011873"],"award-info":[{"award-number":["2019A1515011873"]}]},{"name":"the Medical Project of Science and Technology Planning of Shantou","award":["190413105262902"],"award-info":[{"award-number":["190413105262902"]}]},{"name":"the Medical Project of Science and Technology Planning of Shantou","award":["200605115266724"],"award-info":[{"award-number":["200605115266724"]}]},{"name":"the 2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant","award":["2020LKSFG01B"],"award-info":[{"award-number":["2020LKSFG01B"]}]},{"name":"the Guangdong Esophageal Cancer Institute Science and Technology Program","award":["Q201906"],"award-info":[{"award-number":["Q201906"]}]},{"DOI":"10.13039\/501100001809","name":"the Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81972801"],"award-info":[{"award-number":["81972801"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Objectives: It is reported that inflammation- and nutrition-related indicators have a prognostic impact on multiple cancers. Here we aimed to identify a prognostic nomogram model for prediction of overall survival (OS) in surgical patients with tongue squamous cell carcinoma (TSCC). Methods: The retrospective data of 172 TSCC patients were charted from the Cancer Hospital of Shantou University Medical College between 2008 and 2019. A Cox regression analysis was performed to determine prognostic factors to establish a nomogram and predict OS. The predictive accuracy of the model was analyzed by the calibration curves and the concordance index (C-index). The difference of OS was analyzed by Kaplan\u2013Meier survival analysis. Results: Multivariate analysis showed age, tumor node metastasis (TNM) stage, red blood cell, platelets, and platelet-to-lymphocyte ratio were independent prognostic factors for OS, which were used to build the prognostic nomogram model. The C-index of the model for OS was 0.794 (95% CI\u2009=\u20090.729-0.860), which was higher than that of TNM stage 0.685 (95% CI\u2009=\u20090.605-0.765). In addition, decision curve analysis also showed the nomogram model had improved predictive accuracy and discriminatory performance for OS, compared to the TNM stage. According to the prognostic model risk score, patients in the high-risk subgroup had a lower 5-year OS rate than that in a low-risk subgroup (23% vs 49%, P\u2009&lt;\u2009.0001). Conclusions: The nomogram model based on clinicopathological features inflammation- and nutrition-related indicators represents a promising tool that might complement the TNM stage in the prognosis of TSCC.<\/jats:p>","DOI":"10.1177\/15330338211043048","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T07:40:30Z","timestamp":1638776430000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["A Prognostic Model Based on  Clinicopathological Features and  Inflammation- and Nutrition-Related  Indicators Predicts Overall Survival in  Surgical Patients With Tongue Squamous  Cell Carcinoma"],"prefix":"10.1177","volume":"20","author":[{"given":"Lai-Feng","family":"Wei","sequence":"first","affiliation":[{"name":"The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China"},{"name":"Precision Medicine Research Center, Shantou University Medical College, Shantou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-Chun","family":"Huang","sequence":"additional","affiliation":[{"name":"The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China"},{"name":"Precision Medicine Research Center, Shantou University Medical College, Shantou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Wei","family":"Lin","sequence":"additional","affiliation":[{"name":"The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China"},{"name":"Precision Medicine Research Center, Shantou University Medical College, Shantou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Luo","sequence":"additional","affiliation":[{"name":"The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China"},{"name":"Precision Medicine Research Center, Shantou University Medical College, Shantou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-Yan","family":"Ding","sequence":"additional","affiliation":[{"name":"The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China"},{"name":"Precision Medicine Research Center, Shantou University Medical College, Shantou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can-Tong","family":"Liu","sequence":"additional","affiliation":[{"name":"The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China"},{"name":"Precision Medicine Research Center, Shantou University Medical College, Shantou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4682-0931","authenticated-orcid":false,"given":"Ling-Yu","family":"Chu","sequence":"additional","affiliation":[{"name":"The Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, 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