{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:30:24Z","timestamp":1777941024854,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Suzhou People\u2019s Livelihood Science and Technology Project","award":["SYS2019038"],"award-info":[{"award-number":["SYS2019038"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81601522"],"award-info":[{"award-number":["81601522"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Gusu Health Talent Program","award":["GSWS2020013"],"award-info":[{"award-number":["GSWS2020013"]}]},{"name":"Medical Youth Talent Project of Jiangsu Province","award":["QNRC2016749"],"award-info":[{"award-number":["QNRC2016749"]}]},{"name":"Project of State Key Laboratory of Radiation Medicine and Protection, Soochow University","award":["GZK1202127"],"award-info":[{"award-number":["GZK1202127"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n                    Purpose: In the present study, we mainly aimed to evaluate the prognostic value of 2-deoxy-2-[\n                    <jats:sup>18<\/jats:sup>\n                    F]fluoro-D-glucose ([\n                    <jats:sup>18<\/jats:sup>\n                    F]F-FDG) positron emission tomography (PET)\/computed tomography (CT) after allogeneic stem cell transplantation (allo-SCT) in lymphoblastic lymphoma (LBL) patients using Deauville Scores (DS). Materials and Methods: A total of 63 LBL patients who benefited from\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG PET-CT after allo-SCT in our institution between April 2010 and August 2020 were enrolled in this retrospective study. These above-mentioned patients were divided into two groups based on the Deauville criteria. Diagnostic efficiency of\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG PET\/CT and integrated CT in detecting lymphoma were calculated. Consistencies were evaluated by comparing 18F-FDG PET\/CT and integrated CT results through kappa coefficient. Kaplan-Meier method was used in survival analysis, and the log-rank method was adopted in comparisons. Prognostic factor analysis was performed by the Cox regression model. Results: The sensitivity, specificity, positive predictive value, negative predictive value, accuracy of post-SCT\n                    <jats:sup>18<\/jats:sup>\n                    F-FDG PET-CT were 100%(12\/12), 92.2%(47\/51), 75.0%(12\/16), 100%(47\/47) and 93.7%(59\/63). The consistency of 18F-FDG PET-CT and integrated CT was moderate(Kappa\u2009=\u2009.702\uff0cP\u2009&lt;\u2009.001). Positive post-SCT 18F-FDG PET-CT was associated with lower progression-free survival (PFS) but not overall survival (OS) (p\u2009=\u2009.000 and p\u2009=\u2009.056, respectively). The 3-year PFS of the PET-positive group and PET-negative group was 18.8% and 70.2%, respectively. Multivariate analysis showed that post-SCT PET-CT findings was an independent prognostic factor for PFS (p\u2009=\u2009.000; HR, 3.957; 95%CI, 1.839-8.514). Other factors independently affecting PFS were sex (p\u2009=\u2009.018; HR, 2.588; 95% CI, 1.181\u2009\u2212\u20095.670) and lactate dehydrogenase (LDH) (p\u2009=\u2009.005; HR, 3.246; 95% CI, 1.419\u2009\u2212\u20097.426). However, none of the above-mentioned factors were associated with OS. Conclusions: Collectively, we found that 18F-FDG PET-CT after allo-SCT was a strong indicator for PFS, but not OS, which might provide important evidence for the selection of subsequent treatment regimen for LBL patients. Trial registration number: ChiCTR2100046709.\n                  <\/jats:p>","DOI":"10.1177\/15330338211056478","type":"journal-article","created":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T06:38:21Z","timestamp":1637390301000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Post-transplantation Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography in Patients with Lymphoblastic Lymphoma is an Independent Prognostic Factor with an Impact on Progression-Free Survival but not Overall Survival"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1401-1547","authenticated-orcid":false,"given":"Na","family":"Dai","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengming","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shibiao","family":"Sang","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiwei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,11,20]]},"reference":[{"key":"bibr1-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(17)30445-X"},{"key":"bibr2-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2017.03.020"},{"key":"bibr3-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60605-9"},{"key":"bibr4-15330338211056478","doi-asserted-by":"publisher","DOI":"10.3322\/caac.214385"},{"key":"bibr5-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2008.08.014"},{"key":"bibr6-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705977"},{"key":"bibr7-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2015.332"},{"key":"bibr8-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2008.11.011"},{"key":"bibr9-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2005.07.001"},{"key":"bibr10-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.2403"},{"key":"bibr11-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.8800"},{"key":"bibr12-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx097"},{"key":"bibr13-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24372"},{"key":"bibr14-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.08037.x"},{"key":"bibr15-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-10-388058"},{"key":"bibr16-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-014-2896-2"},{"key":"bibr17-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-021-02551-7"},{"key":"bibr18-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-11-255182"},{"key":"bibr19-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2015142556"},{"key":"bibr20-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2015.05.007"},{"key":"bibr21-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1586\/ehm.10.35"},{"key":"bibr22-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2016.03.034"},{"key":"bibr23-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2014.02.009"},{"key":"bibr24-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1999.17.4.1244"},{"key":"bibr25-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.53.5229"},{"key":"bibr26-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.8044"},{"key":"bibr27-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25957"},{"key":"bibr28-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15793"},{"key":"bibr29-15330338211056478","doi-asserted-by":"publisher","DOI":"10.1177\/0963689720975397"},{"key":"bibr30-15330338211056478","unstructured":"Mehta-Shah N, Teja S, Yu T, et al. 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