{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:30:52Z","timestamp":1777941052237,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Purpose: To compare the diagnostic accuracy and safety of computed tomography (CT)-guided core needle biopsy (CNB) between pulmonary ground-glass and solid nodules using propensity score matching (PSM) method and determine the relevant risk factors. Methods: This was a single-center retrospective cohort study using data from 665 patients who underwent CT-guided CNB of pulmonary nodules in our hospital between May 2019 and May 2021, including 39 ground-glass nodules (GGNs) and 626 solid nodules. We used a 1:4 PSM analysis to compared the diagnostic yields and complications rates of CT-guided CNB between 2 groups. Results: After PSM, 170 cases involved in the comparison (34 GGNs vs 136 solid nodules) were randomly matched (1:4) by patient demographics, clinical history, lesion characteristics, and procedure-related factors. There was no statistically significant difference in the diagnostic yields and complications rates between 2 groups. Significant pneumothorax incidence increase was noted at small lesion size, deep lesion location, and traversing interlobar fissure ( P\u2009&lt;\u2009.05). Post-biopsy hemorrhage was a protective factor for pneumothorax ( P\u2009&lt;\u2009.05). The size\/proportion of consolidation of GGN did not influence the diagnostic accuracy and complication incidence ( P\u2009&gt;\u2009.05). Conclusions: The accuracy and safety of CT-guided CNB were comparable for ground-glass and solid nodules and the size\/proportion of consolidation of GGN may be not a relevant risk factor. The biopsy should avoid traversing interlobar fissure as far as possible. Smaller lesion size and deeper lesion location may lead to higher pneumothorax rate and post-biopsy hemorrhage may be a protective factor for pneumothorax.<\/jats:p>","DOI":"10.1177\/15330338221085357","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T10:40:08Z","timestamp":1647513608000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Comparison of CT-Guided Core Needle Biopsy in Pulmonary Ground-Glass and Solid Nodules Based on Propensity Score Matching Analysis"],"prefix":"10.1177","volume":"21","author":[{"given":"Wenting","family":"An","sequence":"first","affiliation":[{"name":"Zhongnan Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanfei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binchen","family":"Wang","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feiyang","family":"Zhong","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Wang","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9515-6635","authenticated-orcid":false,"given":"Meiyan","family":"Liao","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,17]]},"reference":[{"key":"bibr1-15330338221085357","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2016.03.025"},{"key":"bibr2-15330338221085357","unstructured":"Network NCC. 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