{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:32:11Z","timestamp":1789187531699,"version":"build-2803163510"},"reference-count":24,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T00:00:00Z","timestamp":1659657600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T00:00:00Z","timestamp":1659657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Major Program of Nanjing Medical Science and Technique Development Foundation","award":["ZKX18047"],"award-info":[{"award-number":["ZKX18047"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    To investigate the value of computed tomography-guided percutaneous lung biopsy (CT-PLB) combined with rapid on-site evaluation (ROSE) in the diagnosis of peripheral pulmonary lesions (PPLs).\n                    <jats:bold>Methods:<\/jats:bold>\n                    A total of 108 patients who diagnosed with PPLs by chest CT examination were prospectively collected and randomly divided into ROSE group (n\u2009=\u200956) and No-ROSE group (n\u2009=\u200952). Both groups received CT-PLB and pathological examination. The smear submitted for ROSE was stained using Diff Quik dye. The accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), number of punctures, puncture time and incidence of complications were compared between the two groups.\n                    <jats:bold>Results:<\/jats:bold>\n                    The accuracy, sensitivity, specificity, PPV, and NPV of the ROSE group were 89.29%, 87.50%, 91.67%, 93.33%, and 84.62%, respectively. The number of punctures in the ROSE group was significantly lower than that in the No-ROSE group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.05). The incidence of pneumothorax and hemoptysis in the ROSE group were lower than those in the No-ROSE group, but there was no statistical difference between the two groups (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&gt;\u2009.05). ROSE has good concordance with routine pathological examination in the diagnosis of unidentified PPLs (Kappa\u2009=\u20090.786,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.01).\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    CT-PLB combined with ROSE is a safe and effective method for the diagnosis of PPLs.\n                  <\/jats:p>","DOI":"10.1177\/15330338221118718","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T13:41:07Z","timestamp":1659706867000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["The Value of Computed Tomography-Guided Percutaneous Lung Biopsy Combined With Rapid On-Site Evaluation in Diagnosis of Peripheral Pulmonary Nodules"],"prefix":"10.1177","volume":"21","author":[{"given":"Wei","family":"Liu","sequence":"first","affiliation":[{"name":"Affiliated Nanjing Brain Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8728-2183","authenticated-orcid":false,"given":"Chunhua","family":"Xu","sequence":"additional","affiliation":[{"name":"Affiliated Nanjing Brain Hospital"},{"name":"Nanjing Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Affiliated Nanjing Brain Hospital"},{"name":"Nanjing Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Yuan","sequence":"additional","affiliation":[{"name":"Affiliated Nanjing Brain Hospital"},{"name":"Nanjing Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Affiliated Nanjing Brain Hospital"},{"name":"Nanjing Chest Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jue","family":"Zou","sequence":"additional","affiliation":[{"name":"Affiliated Nanjing Brain Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,8,5]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0300060521999535"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1159\/000430996"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21338"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2017-0114-SA"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.4103\/eus.eus_65_19"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.4103\/1817-1737.124415"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12799"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tgie.2017.10.005"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000489550"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22047"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.11.004"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00111314"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24725"},{"issue":"5","key":"e_1_3_2_15_2","first-page":"406","article-title":"Chinese Expert consensus on issues related to small sample sampling of lung cancer","volume":"55","author":"Respiratory branch of Chinese Medical Association, China lung cancer prevention and treatment alliance","year":"2016","unstructured":"Respiratory branch of Chinese Medical Association, China lung cancer prevention and treatment alliance. Chinese Expert consensus on issues related to small sample sampling of lung cancer. China J Intern Med. 2016;55(5):406\u2010413.","journal-title":"China J Intern Med."},{"issue":"2","key":"e_1_3_2_16_2","first-page":"190","article-title":"Concordance between\u2002rapid\u2002on-site\u2002evaluation\u2002and final cytologic diagnosis in patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration for non-small cell lung cancer staging","volume":"153","author":"Caupena C","year":"2020","unstructured":"Caupena C, Esteban L, Jaen A, et al. Concordance between\u2002rapid\u2002on-site\u2002evaluation\u2002and final cytologic diagnosis in patients undergoing endobronchial ultrasound-guided transbronchial needle aspiration for non-small cell lung cancer staging. Am J Clin Pathol. 2020;153(2):190\u2010197.","journal-title":"Am J Clin Pathol"},{"issue":"1","key":"e_1_3_2_17_2","first-page":"18","article-title":"Rapid on-site evaluation in CT-guided percutaneous biopsy of peripheral pulmonary nodules","volume":"17","author":"Li YY","year":"2020","unstructured":"Li YY, Li KS, Wang X, Shan FC, Li CH. Rapid on-site evaluation in CT-guided percutaneous biopsy of peripheral pulmonary nodules. Chin J Interv Imaging Ther. 2020;17(1):18\u201021.","journal-title":"Chin J Interv Imaging Ther"},{"issue":"10","key":"e_1_3_2_18_2","first-page":"75","article-title":"Exploration on the application of ROSE combined with needle biopsy of lung with guided CT by 4D navigation in the diagnosis of pulmonary diseases","volume":"18","author":"Zhang LT","year":"2021","unstructured":"Zhang LT, Wang J, Zhang Y, Li XH, Wang XL. Exploration on the application of ROSE combined with needle biopsy of lung with guided CT by 4D navigation in the diagnosis of pulmonary diseases. China Medical Equipment. 2021;18(10):75\u201078.","journal-title":"China Medical Equipment"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.4103\/JOC.JOC_134_17"},{"issue":"1","key":"e_1_3_2_20_2","first-page":"51","article-title":"CT Guided fine needle aspiration cytology of thoracic mass lesions: a prospective study of immediate cytological evaluation","volume":"50","author":"Bandyopadhyay A","year":"2007","unstructured":"Bandyopadhyay A, Laha R, Das TK, Sen S, Mangal S, Mitra PK. CT Guided fine needle aspiration cytology of thoracic mass lesions: a prospective study of immediate cytological evaluation. Indian J Pathol Microbiol. 2007;50(1):51\u201055.","journal-title":"Indian J Pathol Microbiol"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.66691"},{"issue":"11","key":"e_1_3_2_22_2","first-page":"1517","article-title":"Efficacy and cost effectiveness of rapid on site examination (ROSE) in management of patients with mediastinal lymphadenopathies","volume":"17","author":"Bruno P","year":"2013","unstructured":"Bruno P, Ricci A, Esposito MC, et al. Efficacy and cost effectiveness of rapid on site examination (ROSE) in management of patients with mediastinal lymphadenopathies. 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