{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:32:48Z","timestamp":1777941168019,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Purpose: The aim of this study was to investigate whether variations in cranial angles and treatment accuracy during CyberKnife robotic radiosurgery necessitate adjustment of the margins of the planning target volume. Patients and Methods: Data from 66 patients receiving CyberKnife treatment for brain tumors were retrospectively analyzed. Patients were immobilized using a thermoplastic mask and headrest. The cranial angle was measured on planning CT and patients were divided into 2 groups: \u226410\u00b0 (Group A) and &gt;10\u00b0 (Group B). Intrafractional motion was recorded using the CyberKnife tracking system over 50\u2005min. Translational and rotational errors were compared between groups, and planning target volume margins were calculated. Results: In Group A, significant translational error differences were found along with the X-axis over time ( P\u2009&lt;\u2009.02). In Group B, significant differences occurred along with the Z-axis ( P\u2009&lt;\u2009.03). No significant rotational or 3-dimensional vector differences were found in either group. Group A had significantly lower Y-axis ( P\u2009&lt;\u2009.045) and roll axis ( P\u2009&lt;\u2009.005) errors compared to Group B. Estimated planning target volume margins in Group A were 0.56 mm (X), 0.46 mm (Y), and 0.47 mm (Z). In Group B, margins were 0.62 mm (X), 0.48 mm (Y), and 0.46 mm (Z). Margins covering 95% of intrafraction motion were 0.49 to 0.50 mm (X, Y, Z) and 0.69 mm (3-dimensional vector) for Group A, and 0.48 to 0.60 mm and 0.79 mm for Group B. With a 1-mm margin, complete coverage was achieved in Group A while 2.1% of vectors in Group B exceeded 1 mm. Conclusion: Adjusting cranial angle to \u226410\u00b0 during thermoplastic mask molding provided better or similar intrafractional stability compared to &gt;10\u00b0.<\/jats:p>","DOI":"10.1177\/15330338241235058","type":"journal-article","created":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T19:49:00Z","timestamp":1710013740000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Patient Cranial Angle and Intrafractional Stability in CyberKnife Robotic Radiosurgery: A Retrospective Analysis"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6388-948X","authenticated-orcid":false,"given":"Chen-Lin","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;"},{"name":"Department of Medical Imaging and Radiology, Shu-Zen Junior College of Medicine and Management, Kaohsiung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-Yu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Ren","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Huei","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6044-1498","authenticated-orcid":false,"given":"Chun-Chieh","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Jie","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,3,9]]},"reference":[{"key":"bibr1-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2009.12.030"},{"key":"bibr2-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.01.008"},{"key":"bibr3-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.01.052"},{"key":"bibr4-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2007.05.097"},{"key":"bibr5-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2011.12.003"},{"key":"bibr6-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-019-1425-7"},{"key":"bibr7-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.03.006"},{"key":"bibr8-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2007.05.030"},{"key":"bibr9-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2004.08.002"},{"key":"bibr10-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2011.10.012"},{"key":"bibr11-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.13143"},{"issue":"359","key":"bibr12-15330338241235058","volume":"8","author":"Kang C-L","year":"2018","journal-title":"Front Oncol."},{"key":"bibr13-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(00)00280-2"},{"key":"bibr14-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00518-6"},{"key":"bibr15-15330338241235058","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"bibr16-15330338241235058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2010.06.022"}],"container-title":["Technology in Cancer Research &amp; 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