{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:11:06Z","timestamp":1790737866885,"version":"4.1.0"},"reference-count":24,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To improve the setup reproducibility of neck curvature using real-time optical surface imaging (OSI) guidance on 2 regions of interest (ROIs) to infer cervical spine (c-spine) curvature for surface-guided radiotherapy (SGRT) of head-and-neck (HN) and c-spine cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A novel SGRT setup approach was designed to reproduce neck curvature with 2 ROIs: upper-chest ROI and open-face ROI. It was hypothesized that the neck curvature could be reproduced if both ROIs were aligned within \u00b13 mm\/2\u02da tolerance. This was tested prospectively in 7 volunteers using real-time 3D-OSI guidance and lateral 2D-photography verification after the 3D and 2D references were captured from the initial conventional setup. Real-time SGRT was performed to align chest-ROI and face-ROI, and the longitudinal distance between them was adjustable using a head-support slider. Verification of neck curvature anteriorly and posteriorly was achieved by overlaying edge-extracted lateral pictures. Retrospectively, the relationship between anterior surface and spinal canal alignment was checked in 11 patients using their simulation CT (simCT) and setup cone-beam CT (CBCT). After the anterior surface was rigidly aligned, the spinal canal alignment was checked and quantified using the mean-distance-to-agreement (MDA) and DICE similarity index, and surface-to-spine correlation was calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The reproducibility of neck curvatures using the 2xROI SGRT setup is verified and the mean neck-outline-matching difference is within \u00b12 mm in lateral photographic overlays. The chest-ROI alignment takes 110\u2009\u00b1\u200958 s and the face-ROI takes 60\u2009\u00b1\u200935 s. When the anterior body surface is aligned (MDA\u2009=\u20091.1\u2009\u00b1\u20090.6 mm, DICE\u2009=\u20090.96\u2009\u00b1\u20090.02,) the internal spinal canal is also aligned (MDA\u2009=\u20091.0\u2009\u00b1\u20090.3 mm, DICE\u2009=\u20090.84\u2009\u00b1\u20090.04) in 11 patients. The surface-to-spine correlation is c\u2009=\u20090.90 (MDA) and c\u2009=\u20090.85 (DICE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates the feasibility of the novel 2-ROI SGRT setup technique to achieve reproducible neck and c-spine curvature regardless of neck visibility and availability as ROI. Staff training is needed to adopt this unconventional SGRT technique to improve patient setup.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15330338241271946","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T07:25:00Z","timestamp":1723015500000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Feasibility of a Novel Surface-Guided Setup Technique to Reproduce Neck Curvature Using two Regions of Interest"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9022-2883","authenticated-orcid":false,"given":"Guang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlyn","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Gil","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar Della","family":"Biancia","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,7]]},"reference":[{"key":"bibr1-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2017.12.007"},{"key":"bibr2-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.semradonc.2017.03.004"},{"key":"bibr3-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2019.09.038"},{"key":"bibr4-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1177\/153303460700600306"},{"key":"bibr5-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.12.039"},{"key":"bibr6-15330338241271946","first-page":"120","volume":"18","author":"Joint H","year":"2019","journal-title":"Clin Transl Radiat Oncol"},{"key":"bibr7-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1118\/1.4905050"},{"key":"bibr8-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.09.020"},{"key":"bibr9-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1111\/1754-9485.12968"},{"key":"bibr10-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.semradonc.2018.02.003"},{"key":"bibr11-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1118\/1.3596526"},{"key":"bibr12-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.13241"},{"key":"bibr13-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.12762"},{"issue":"16","key":"bibr14-15330338241271946","first-page":"1","volume":"67","author":"Li G","year":"2022","journal-title":"Phys Med Biol."},{"key":"bibr15-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v16i4.5416"},{"key":"bibr16-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.radi.2020.02.008"},{"key":"bibr17-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.12557"},{"key":"bibr18-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/54\/22\/007"},{"key":"bibr19-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1002\/mp.13816"},{"key":"bibr20-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1002\/mp.12217"},{"key":"bibr21-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.prro.2013.09.001"},{"key":"bibr22-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.12.004"},{"key":"bibr23-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1002\/acm2.12867"},{"key":"bibr24-15330338241271946","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-43740-4_20"}],"container-title":["Technology in Cancer Research &amp; Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15330338241271946","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15330338241271946","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15330338241271946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:15:14Z","timestamp":1777702514000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15330338241271946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":24,"alternative-id":["10.1177\/15330338241271946"],"URL":"https:\/\/doi.org\/10.1177\/15330338241271946","relation":{},"ISSN":["1533-0346","1533-0338"],"issn-type":[{"value":"1533-0346","type":"print"},{"value":"1533-0338","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"15330338241271946"}}