{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:33:20Z","timestamp":1777941200715,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Jiangsu Provincial Natural Science Foundation General Project","award":["BK20231190"],"award-info":[{"award-number":["BK20231190"]}]},{"name":"General Program of National Natural Science Foundation of China","award":["62371243"],"award-info":[{"award-number":["62371243"]}]},{"name":"Jiangsu Provincial Key Research and Development Program Social Development Project","award":["BE2022720"],"award-info":[{"award-number":["BE2022720"]}]},{"name":"Jiangsu Provincial Medical Key Discipline (Laboratory) Cultivation Unit","award":["JSDW202237"],"award-info":[{"award-number":["JSDW202237"]}]},{"name":"Changzhou Social Development Project","award":["CE20235063"],"award-info":[{"award-number":["CE20235063"]}]},{"name":"Jiangsu Provincial Health Commission General Project","award":["M2020006"],"award-info":[{"award-number":["M2020006"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Part of the tumor localization methods in radiotherapy have poor real-time performance and may generate additional radiation. We propose a multimodal point cloud-based method for tumor localization in robotic ultrasound-guided radiotherapy, which only irradiates computed tomography (CT) during radiotherapy planning to avoid additional radiation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The tumor position was determined using the CT point cloud, and the red green blue depth (RGBD) point cloud was used to determine body surface scanning location corresponding to the tumor location. The relationship between the CT point cloud and RGBD point cloud was established through multi-modal point cloud registration. The point cloud was then used for robot tumor localization through coordinate transformation between camera and robot.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The maximum mean absolute error of the tumor location in the X, Y, and Z directions of the robot coordinate system were 0.781, 1.334, and 1.490\u2005mm, respectively. The average point-to-point translation mean absolute error between the actual and predicted positions of the localization points was 1.847\u2005mm. The maximum error in the random positioning experiment was 1.77\u2005mm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The proposed method is radiation free and has real-time performance, with tumor localization accuracy that meets the requirements of radiotherapy. The proposed method, which potentially reduces the risks associated with radiation exposure while ensuring efficient and accurate tumor localization, represents a promising advancement in the field of radiotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15330338241273149","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T03:15:22Z","timestamp":1724037322000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A Multimodal Point Cloud-Based Method for Tumor Localization in Robotic Ultrasound-Guided Radiotherapy"],"prefix":"10.1177","volume":"23","author":[{"given":"Lintao","family":"Song","sequence":"first","affiliation":[{"name":"Department of Radiotherapy, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou, China"},{"name":"Jiangsu Province Engineering Research Center of Medical Physics, Changzhou, 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Engineering Research Center of Medical Physics, Changzhou, China"},{"name":"Center for Medical Physics, Nanjing Medical University, Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kangkang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou, China"},{"name":"Jiangsu Province Engineering Research Center of Medical Physics, Changzhou, China"},{"name":"Center for Medical Physics, Nanjing Medical University, Changzhou, China"},{"name":"School of Computer and Artificial Intelligence, Changzhou University, Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou, China"},{"name":"Jiangsu Province Engineering Research Center 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China"},{"name":"Jiangsu Province Engineering Research Center of Medical Physics, Changzhou, China"},{"name":"Center for Medical Physics, Nanjing Medical University, Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuqing","family":"Jiao","sequence":"additional","affiliation":[{"name":"School of Microelectronics and Control Engineering, Changzhou University, Changzhou, China"},{"name":"School of Computer and Artificial Intelligence, Changzhou University, Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2402-9719","authenticated-orcid":false,"given":"Xinye","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The Affiliated Changzhou NO.2 People's Hospital of Nanjing Medical University, Changzhou, China"},{"name":"Jiangsu Province Engineering Research Center of Medical Physics, Changzhou, China"},{"name":"Center for Medical Physics, Nanjing Medical 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