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Traditional imaging modalities, such as 18F-fluorodeoxyglucose positron emission tomography\/computed tomography (18F-FDG-PET\/CT) and contrast-enhanced CT, are standard for staging and monitoring but expose patients to ionizing radiation, increasing the risk of secondary malignancies. This review evaluates whole-body magnetic resonance imaging (WB-MRI) as a radiation-free alternative for assessing lymphoproliferative disorders. We examine its strengths, including the ability to detect disease and assess treatment response, as well as its limitations, such as challenges in visualizing small thoracic lesions. Recent studies demonstrate high concordance between WB-MRI and 18F-FDG-PET\/CT, particularly for lymphomas with low or variable FDG avidity, making WB-MRI a promising modality for staging and follow-up, especially in young and pregnant patients.<\/jats:p>","DOI":"10.1177\/15330338251359724","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T06:56:39Z","timestamp":1755500199000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Role of Whole-Body MRI in Patients with Lymphoma: A Narrative Review"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6578-775X","authenticated-orcid":false,"given":"Benedetta","family":"Renzetti","sequence":"first","affiliation":[{"name":"Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9574-586X","authenticated-orcid":false,"given":"Arrigo","family":"Cattabriga","sequence":"additional","affiliation":[{"name":"Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy"},{"name":"Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7563-8936","authenticated-orcid":false,"given":"Stefano","family":"Brocchi","sequence":"additional","affiliation":[{"name":"Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3849-8428","authenticated-orcid":false,"given":"Caterina","family":"Gaudiano","sequence":"additional","affiliation":[{"name":"Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8222-1512","authenticated-orcid":false,"given":"Marta","family":"Assenza","sequence":"additional","affiliation":[{"name":"Professional development and implementation of research in health professions unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2000-1599","authenticated-orcid":false,"given":"Cristina","family":"Nanni","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5633-7313","authenticated-orcid":false,"given":"Alessandro","family":"Broccoli","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy"},{"name":"Istituto di Ematologia \u201cSer\u00e0gnoli\u201d, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Basile","sequence":"additional","affiliation":[{"name":"Radiology I Unit, Policlinico Universitario G. 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