{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:54:57Z","timestamp":1780728897924,"version":"3.54.1"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Breast cancer remains a leading cause of cancer mortality despite being potentially curable when detected early, particularly in low- and middle-income countries where access to screening is limited. This is largely driven by operational gaps, including limited access to screening and delays in diagnosis and treatment. JULIETA is a portable bioimpedance spectroscopy device designed to identify electrical tissue patterns associated with potentially malignant findings and to prioritize women for further diagnostic evaluation. This study assessed the performance of a hierarchical algorithm integrated into JULIETA to distinguish findings without malignant potential (BI-RADS 1-2) from those with malignant potential (BI-RADS \u22653), using mammography as the reference standard.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional observational study with prospective data collection was conducted between May and July 2024 in four Colombian cities. Adult women undergoing screening or follow-up mammography were evaluated with JULIETA prior to imaging. Impedance-derived features, breast density estimates, and individual risk scores were used to retrain a hierarchical classifier combining Random Forest and SVM-RBF models, using an 80\/20 stratified split and cross-validation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1350 women were recruited (mean age 56.5\u2009\u00b1\u20098.0 years); 67% were BI-RADS 1-2 and 21% BI-RADS 4. After data cleaning, 673 breasts (469 women) were included. The model achieved 73% sensitivity, 76% specificity, 65.5% positive predictive value, and 82.1% negative predictive value.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>JULIETA is a feasible, safe, and reproducible noninvasive bioimpedance pre-screening tool that may enable scalable triage and support earlier detection and improved equity when integrated into public health pathways.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15330338261422902","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T17:48:28Z","timestamp":1770832108000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Portable Electrical Impedance Prescreening for Breast tissue suspicious for malignancy: Model Optimization and Clinical Performance of the Julieta Device in a Multicenter Cross-Sectional Study in Colombia"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1746-5176","authenticated-orcid":false,"given":"Maria Andrea","family":"Negret","sequence":"first","affiliation":[{"name":"Pontifical Xavierian University"},{"name":"Clinical Specialist, SalvaHealth, Medell\u00edn, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2694-7970","authenticated-orcid":false,"given":"Valentina","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Los Andes University"},{"name":"Research and Development Engineer, SalvaHealth, Medell\u00edn, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0611-4549","authenticated-orcid":false,"given":"David","family":"Grajales","sequence":"additional","affiliation":[{"name":"Polytechnic Montreal Louise-Lalonde-Lamarre Library"},{"name":"Head of Artificial Intelligence, SalvaHealth, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3151-3992","authenticated-orcid":false,"given":"Maria Alejandra","family":"Velez","sequence":"additional","affiliation":[{"name":"EAFIT University"},{"name":"Artificial Intelligence Engineer, SalvaHealth, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5309-814X","authenticated-orcid":false,"given":"Maria Alejandra","family":"Yepez","sequence":"additional","affiliation":[{"name":"Antioquia School of Engineering University"},{"name":"Artificial Intelligence Engineer, SalvaHealth, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3889-130X","authenticated-orcid":false,"given":"Valentina","family":"Agudelo","sequence":"additional","affiliation":[{"name":"CESA University (Colegio de estudios superiores de administraci\u00f3n)"},{"name":"Chief Executive Officer, SalvaHealth, Medell\u00edn, Bogot\u00e1, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9640-5605","authenticated-orcid":false,"given":"Sergio","family":"Lopez","sequence":"additional","affiliation":[{"name":"CES University (Corporaci\u00f3n en estudios de la salud) Bogot\u00e1"},{"name":"Chief Technology Officer, SalvaHealth, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Piedrahita","sequence":"additional","affiliation":[{"name":"CES University (Corporaci\u00f3n en estudios de la salud) Bogot\u00e1"},{"name":"Centro de Biociencias, Seguros SURA, Medell\u00edn, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"e_1_3_4_2_2","volume-title":"Breast cancer. 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