{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T08:09:01Z","timestamp":1779091741624,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Technol Cancer Res Treat"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim of this research is to examine the impact of neuromuscular electrical stimulation (NMES) and early mobilization (EM) on preventing the intensive care unit-acquired weakness (ICU-AW) in lung cancer resection patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a single-center, parallel-group, randomized controlled trial. Participants were randomized into NMES, EM, and control groups. The main outcome measure was the occurrence of ICU-AW, with secondary outcomes encompassing differences in handgrip strength, duration of stay in the ICU, and overall hospital length of stay across the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both interventions demonstrated significant reductions in ICU-AW incidence compared with the control group. The EM group had odds ratios of 0.10 (95% CI 0.03 - 0.31) at 2 days post-admission and 0.07 (95% CI 0.02 - 0.26) at ICU discharge, while the NMES group showed comparable reductions (OR 0.07; 95% CI 0.02 - 0.23 and OR 0.02; 95% CI 0.00 - 0.18, respectively). No significant between-intervention differences were observed. Compared with the control group, both intervention groups showed significantly greater handgrip strength at two days after ICU admission and at ICU discharge (P &lt; 0.05). Neither intervention significantly affected ICU or hospital length of stay (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EM and NMES each play a significant role in the reduction of ICU-AW incidence, enhance the handgrip strength of both upper limbs, but do not reduce ICU or hospital length of stay in lung cancer resection patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15330338261452889","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T18:47:09Z","timestamp":1778870829000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of Early Neuromuscular Electrical Stimulation and Early Mobilization on Preventing the Intensive Care Unit-Acquired Weakness in Lung Cancer Resection Patients: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"25","author":[{"given":"Jun","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, Pingshan District Central Hospital of Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihua","family":"Huang","sequence":"additional","affiliation":[{"name":"Clinical Nursing Teaching and Research Section, The Second Xiangya Hospital of Central South University, Changsha, China"},{"name":"Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunna","family":"Lan","sequence":"additional","affiliation":[{"name":"The Second Xiangya Hospital of Central South University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Pingshan District Central Hospital of Shenzhen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiling","family":"Hu","sequence":"additional","affiliation":[{"name":"The Hong Kong Polytechnic University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzhou","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, Shanghai Pudong New District Zhoupu Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aierken","family":"Nilubaier","sequence":"additional","affiliation":[{"name":"John G. 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