{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:24:14Z","timestamp":1791246254181,"version":"4.1.0"},"reference-count":35,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,2,26]],"date-time":"2009-02-26T00:00:00Z","timestamp":1235606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2009,6]]},"abstract":"<jats:p>The authors present findings from a behavioral task (visual paired comparison) using infrared eye-tracking that could potentially be useful in predicting the onset of Alzheimer's disease. Delay intervals of 2 seconds and 2 minutes were used between the initial viewing of a picture and when the picture was displayed alongside a novel picture. Eye-tracking revealed that at the 2-second delay, 6 patients with mild cognitive impairment, 15 matched control participants (normal control), and 4 neurological control participants with Parkinson's disease performed comparably, viewing the novel picture greater than 71% of the time. When the delay increased to 2 minutes, patients with mild cognitive impairment viewed the novel picture only 53% of the time (P &lt; .05), while control participants and participants with Parkinson's disease remained above 70%. These findings demonstrate the usefulness of this task for assessing normal as well as impaired memory function.<\/jats:p>","DOI":"10.1177\/1533317509332093","type":"journal-article","created":{"date-parts":[[2009,2,26]],"date-time":"2009-02-26T21:22:27Z","timestamp":1235683347000},"page":"258-266","source":"Crossref","is-referenced-by-count":143,"title":["Eye Tracking During a Visual Paired Comparison Task as a Predictor of Early Dementia"],"prefix":"10.1177","volume":"24","author":[{"given":"Michael D.","family":"Crutcher","sequence":"first","affiliation":[{"name":"Yerkes National Primate Research Center, Emory University, Emory Alzheimer's Disease Research Center, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Calhoun-Haney","sequence":"additional","affiliation":[{"name":"Yerkes National Primate Research Center, Emory University, Emory Alzheimer's Disease Research Center, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecelia M.","family":"Manzanares","sequence":"additional","affiliation":[{"name":"Yerkes National Primate Research Center, Emory University, Emory Alzheimer's Disease Research Center, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"Lah","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Emory Alzheimer's Disease Research Center, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan I.","family":"Levey","sequence":"additional","affiliation":[{"name":"Emory Center for Neurodegenerative Disease, Emory University School of Medicine, Emory Alzheimer's Disease Research Center, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart M.","family":"Zola","sequence":"additional","affiliation":[{"name":"Yerkes National Primate Research Center (Director), Emory University, Emory Alzheimer's Disease Research Center, Veterans Administration Medical Center, Atlanta, Georgia,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,2,26]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.56.3.303"},{"key":"atypb2","first-page":"9","author":"Morris JC","year":"2005","journal-title":"Geriatrics"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.9.1133"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11920-9"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1007\/BF00308809"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(97)00062-6"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(01)00365-5"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1126\/science.1896849"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.6.808"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1995.00540290075020"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/0022-0965(70)90087-1"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1037\/11164-000"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.2.320"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1037\/0096-1523.4.4.565"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-23-08853.2000"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1037\/0278-7393.19.2.397"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.220398097"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199301000-00020"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-01-00451.2000"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1990.tb48902.x"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1002\/dev.10161"},{"key":"atypb22","first-page":"58","volume":"12","author":"Daffner KR","year":"1999","journal-title":"Neuropsychiatry Neuropsychol Behav Neurol"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh484"},{"key":"atypb24","volume-title":"Clock Drawing: A Neuropsychological Analysis","author":"Freedman M.","year":"1994"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.3.181"},{"key":"atypb26","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3071-06.2006"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199810083391506"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199810153391607"},{"issue":"5","key":"atypb29","first-page":"845","volume":"109","author":"Taylor AE","year":"1986","journal-title":"The cortical focus of neostriatal outflow. 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