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The purpose of this paper is to develop a conceptual model to guide future aerobic exercise research and practice by synthesizing the current state of the science on aerobic exercise training in older adults with AD. The literature review found 12 qualified studies that met the eligibility criteria for inclusion in this review and revealed six constructs (aerobic exercise training, physical fitness, physical performance, activities of daily living limitations, cognition, and psychological and behavioral symptoms), which composed the Functional Impact of aerobic exercise Training in Alzheimer\u2019s disease (FIT-AD) model. The state of science on each construct in older adults with Alzheimer\u2019s disease is reviewed and summarized. The emerging evidence suggests that aerobic exercise training might positively impacts all five other constructs. The implications of the FIT-AD model for future research and practice are discussed highlighted<\/jats:p>","DOI":"10.1177\/1533317511402317","type":"journal-article","created":{"date-parts":[[2011,3,23]],"date-time":"2011-03-23T20:36:52Z","timestamp":1300912612000},"page":"184-194","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":36,"title":["Guiding Research and Practice: A Conceptual Model for Aerobic Exercise Training in Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"26","author":[{"family":"Fang Yu","sequence":"first","affiliation":[{"name":"University of Minnesota School of Nursing, Minneapolis, Minnesota, 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