{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T18:36:19Z","timestamp":1781894179157,"version":"3.54.5"},"reference-count":36,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2011,6,29]],"date-time":"2011-06-29T00:00:00Z","timestamp":1309305600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:p>We examined retrospectively the concurrent relationships between fasting plasma total cholesterol, triglycerides, and glucose levels, and Alzheimer\u2019s disease (AD), in a clinical setting-based study. Total cholesterol level was higher in patients with AD compared to elderly controls; triglycerides or glucose levels did not significantly differ between the 2 groups. Respective plotted trajectories of change in cholesterol level across age were fairly parallel. No significant difference in total cholesterol levels was recorded between patients with AD classified by the Clinical Dementia Rating (CDR) score subgroups. These results suggest that patients with AD have relative mild total hypercholesterolemia, normal triglyceridemia, and normal fasting plasma glucose level. Mild total hypercholesterolemia seems to be permanent across age, and across dementia severity staging, and fairly parallels the trajectory of age-related change in total cholesterolemia of healthy controls. We speculate that these biochemical parameters pattern may be present long before\u2014a decade at least\u2014the symptomatic onset of the disease.<\/jats:p>","DOI":"10.1177\/1533317511414552","type":"journal-article","created":{"date-parts":[[2011,6,29]],"date-time":"2011-06-29T20:56:44Z","timestamp":1309381004000},"page":"399-405","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Mild Hypercholesterolemia, Normal Plasma Triglycerides, and Normal Glucose Levels Across Dementia Staging in Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"26","author":[{"given":"Said","family":"Ramdane","sequence":"first","affiliation":[{"name":"Private Practice Office of Neurology, Skikda, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doria","family":"Daoudi-Gueddah","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Skikda, Skikda, 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