{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:24:44Z","timestamp":1784589884271,"version":"3.55.0"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2012,7,19]],"date-time":"2012-07-19T00:00:00Z","timestamp":1342656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>Herein we describe 6 cases of patients with Alzheimer\u2019s disease presented with syncope, dizziness, and dyspnea soon after the initiation of cholinesterase inhibitor therapy. All patients had bradyarrhythmia on electrocardiogram (ECG). Two patients had complete atrioventricular block, 2 pateints had 2\/1 type atrioventricular block, 1 patient had sinus bradycardia and hypersensitive carotid sinus syndrome, and 1 had sick sinus syndrome. All these patients were treated with pacemaker implantation and the cholinesterase inhibitor therapy continued. At 13-month follow-up, no syncope, dizziness, or dyspnea was reported.<\/jats:p>","DOI":"10.1177\/1533317512452040","type":"journal-article","created":{"date-parts":[[2012,7,19]],"date-time":"2012-07-19T10:00:03Z","timestamp":1342692003000},"page":"311-314","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Anticholinesterase-Induced Symptoms Improved by Pacemaker Implantation in Patients With Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"27","author":[{"given":"Damirbek","family":"Osmonov","sequence":"first","affiliation":[{"name":"Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazim Serhan","family":"\u00d6zcan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izzet","family":"Erdinler","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Servet","family":"Altay","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceyhan","family":"Turkkan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ersin","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadir","family":"Gurkan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,7,19]]},"reference":[{"key":"bibr1-1533317512452040","unstructured":"American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Text Revision. Washington, DC: American Psychiatric Association; 2000:147\u201358."},{"key":"bibr2-1533317512452040","author":"NICE Technology Appraisal","year":"2011","journal-title":"Alzheimer's Disease\u2014Donepezil, Galantamine, Rivastigmine and Memantine (Review): Final Appraisal Determination"},{"key":"bibr3-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1126\/science.1132813"},{"key":"bibr4-1533317512452040","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200161010-00005"},{"key":"bibr5-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1998.tb04467.x"},{"key":"bibr6-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.1.94"},{"key":"bibr7-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1159\/000017259"},{"key":"bibr8-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.12.2269"},{"key":"bibr9-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1097\/00002093-200001000-00005"},{"key":"bibr10-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(98)00019-3"},{"issue":"11","key":"bibr11-1533317512452040","first-page":"1070","volume":"28","author":"Calvo-Romero JM","year":"1999","journal-title":"Rev Neurol"},{"key":"bibr12-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1345\/aph.18273"},{"key":"bibr13-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/27.3.453"},{"issue":"3","key":"bibr14-1533317512452040","first-page":"145","volume":"105","author":"Ellis JM","year":"2005","journal-title":"J Am Osteopath Assoc"},{"issue":"10","key":"bibr15-1533317512452040","first-page":"563","volume":"150","author":"Leentjens AF","year":"2006","journal-title":"Ned Tijdschr Geneeskd"},{"key":"bibr16-1533317512452040","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp070230"},{"key":"bibr17-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1016\/S1099-5129(03)00080-1"},{"key":"bibr18-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2009.02488.x"},{"key":"bibr19-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1038\/nm0706-780"},{"key":"bibr20-1533317512452040","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2011.69"}],"container-title":["American Journal of Alzheimer's Disease &amp; Other Dementias\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1533317512452040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1533317512452040","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1533317512452040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:23:03Z","timestamp":1777368183000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1533317512452040"}},"subtitle":["Analysis of 6 Cases"],"short-title":[],"issued":{"date-parts":[[2012,7,19]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["10.1177\/1533317512452040"],"URL":"https:\/\/doi.org\/10.1177\/1533317512452040","relation":{},"ISSN":["1533-3175","1938-2731"],"issn-type":[{"value":"1533-3175","type":"print"},{"value":"1938-2731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,19]]}}}