{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:17:44Z","timestamp":1777382264116,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T00:00:00Z","timestamp":1369267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p>We examined initiation of cholinesterase inhibitors (ChEIs) to determine whether ChEIs were being newly prescribed without sufficient evaluation for dementia and\/or delirium and to explore whether there are differences in outcomes, such as mortality, hospital readmission rates, and duration of hospitalization, between patients newly started on ChEI and those who continued such medications prior to admission. Patients hospitalized in fiscal year 2008 and prescribed ChEI were identified. We reviewed electronic medical records. Of 282 patients, 15.6% (44) were new-starts and 84.4% (238) were continuations. Median length of stay was 16 days in new-starts versus 6 days in continuations ( P &lt; .05). Of new-starts, 38.6% were also treated of infection. Chart review additionally suggested possible treatment of delirium by initiation of benzodiazepines and antipsychotics in 11.4% and 22.7% of new-starts, respectively. We observed a substantive practice of initiating ChEIs in hospitalized elderly patients at risk of delirium. Although there was no difference in the 30-day mortality or readmission rates, new-starts were more likely to have a longer hospital stay than continuation patients.<\/jats:p>","DOI":"10.1177\/1533317513488909","type":"journal-article","created":{"date-parts":[[2013,5,24]],"date-time":"2013-05-24T01:11:07Z","timestamp":1369357867000},"page":"377-383","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Initiation of Cholinesterase Inhibitors in an Inpatient Setting"],"prefix":"10.1177","volume":"28","author":[{"given":"Kamal C.","family":"Wagle","sequence":"first","affiliation":[{"name":"Houston VA HSR&D Center of Excellence, Michael E. DeBakey Veterans Affairs Medical Center (MEDVAMC), Houston, TX, USA"},{"name":"Department of Family and Community Medicine, Baylor College of Medicine, Houston, TX, USA"},{"name":"Extended Care Line, Michael E. DeBakey VA Medical Center, Houston, TX, USA"},{"name":"Management, Policy and Community Health, The University of Texas School of Public Health, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Rowan","sequence":"additional","affiliation":[{"name":"Management, Policy and Community Health, The University of Texas School of Public Health, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oi-Yee Ivy","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Baylor College of Medicine, Houston, TX, USA"},{"name":"Extended Care Line, Michael E. DeBakey VA Medical Center, Houston, TX, USA"},{"name":"College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX, USA"},{"name":"Department of Medicine, Section of Geriatrics, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark E.","family":"Kunik","sequence":"additional","affiliation":[{"name":"Houston VA HSR&D Center of Excellence, Michael E. DeBakey Veterans Affairs Medical Center (MEDVAMC), Houston, TX, USA"},{"name":"VA South Central Mental Illness Research, Education and Clinical Center, USA"},{"name":"Menninger Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA"},{"name":"Department of Medicine, Health Services Research, Baylor College of Medicine, Houston, TX, USA"},{"name":"Mental Health Care Line, Michael E DeBakey VA Medical Center, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George E.","family":"Taffet","sequence":"additional","affiliation":[{"name":"Houston VA HSR&D Center of Excellence, Michael E. DeBakey Veterans Affairs Medical Center (MEDVAMC), Houston, TX, USA"},{"name":"Department of Family and Community Medicine, Baylor College of Medicine, Houston, TX, USA"},{"name":"Extended Care Line, Michael E. DeBakey VA Medical Center, Houston, TX, USA"},{"name":"Department of Medicine, Section of Geriatrics, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula K.","family":"Braun","sequence":"additional","affiliation":[{"name":"Houston VA HSR&D Center of Excellence, Michael E. DeBakey Veterans Affairs Medical Center (MEDVAMC), Houston, TX, USA"},{"name":"Extended Care Line, Michael E. DeBakey VA Medical Center, Houston, TX, USA"},{"name":"Department of Medicine, Section of Geriatrics, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,5,23]]},"reference":[{"key":"bibr1-1533317513488909","unstructured":"Russo AC, Elixhauser A. Statistical brief #6. Hospitalizations in the elderly population, 2003. 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