{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:14:07Z","timestamp":1787019247493,"version":"build-2736575974"},"reference-count":19,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2014,5,26]],"date-time":"2014-05-26T00:00:00Z","timestamp":1401062400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Rivastigmine is commonly used for the treatment of Alzheimer\u2019s disease (AD). All cholinesterase inhibitors, including rivastigmine, may cause cardiac side effects. The aim of this study is to compare the electrocardiographic (ECG) and hypotensive effects of formulations of rivastigmine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Eighty-five newly diagnosed patients with AD who were treated with rivastigmine were retrospectively evaluated. The ECG records were reviewed at baseline and at administration of either 12 mg of oral rivastigmine or 10 cm\n                      <jats:sup>2<\/jats:sup>\n                      transdermal rivastigmine.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>When compared with the baseline, there were no changes in any of the ECG parameters in all of the patients ( P &gt; .05). Moreover, when compared with the mean change from baseline for each treatment group, there were no changes, except heart rate ( P = .035).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>It was demonstrated that rivastigmine formulations were not associated with increased arrhythmogenic or hypotensive effects in elderly patients with AD and was not superior to each other.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1533317514536598","type":"journal-article","created":{"date-parts":[[2014,5,27]],"date-time":"2014-05-27T20:31:53Z","timestamp":1401222713000},"page":"735-738","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Which Rivastigmine Formula is Better for Heart in Elderly Patients With Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"29","author":[{"given":"Ahmet Turan","family":"Isik","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine, School of Medicine, Dokuz Eylul University, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinar","family":"Soysal","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, School of Medicine, Dokuz Eylul University, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Yay","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,5,26]]},"reference":[{"key":"bibr1-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2009.02330.x"},{"key":"bibr2-1533317514536598","doi-asserted-by":"publisher","DOI":"10.2174\/1567205043332009"},{"key":"bibr3-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afm002"},{"key":"bibr4-1533317514536598","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp070230"},{"key":"bibr5-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.180.5.466-a"},{"issue":"1","key":"bibr6-1533317514536598","first-page":"113","volume":"10","author":"Knudtzen FC","year":"2013","journal-title":"J Geriatr Cardiol"},{"key":"bibr7-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1177\/1533317512442999"},{"key":"bibr8-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1177\/00912700222011490"},{"key":"bibr9-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1002\/gps.1788"},{"key":"bibr10-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000281847.17519.e0"},{"key":"bibr11-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1185\/030079907X233403"},{"key":"bibr12-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1159\/000345989"},{"key":"bibr13-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.7.939"},{"key":"bibr14-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000163132.84890.c4"},{"key":"bibr15-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.1997.tb00325.x"},{"key":"bibr16-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.08.067"},{"key":"bibr17-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1998.1094"},{"key":"bibr18-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1378\/chest.81.3.302"},{"key":"bibr19-1533317514536598","doi-asserted-by":"publisher","DOI":"10.1192\/apt.bp.106.002725"}],"container-title":["American Journal of Alzheimer's Disease &amp; 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