{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:59:02Z","timestamp":1777381142774,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T00:00:00Z","timestamp":1412208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The study was undertaken to evaluate the postganglionic sympathetic sudomotor function employing the quantitative sudomotor axon reflex test (QSART) in tauopathies Alzheimer\u2019s disease (AD) and behavioral variant of frontotemporal dementia (bvFTD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients were recruited in a prospective pilot study. A structured history was taken and QSART was recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In all, 15 patients with AD (7 female) and 14 patients with bvFTD (9 female) were included. Mean age (\u00b1standard deviation) of patients with AD and bvFTD was 74 \u00b1 9 and 71 \u00b1 10 years, respectively. Severe sudomotor dysfunction (Composite Autonomic Severity sudomotor score 3) was present in 3 (20%) patients with AD and 0 (0%) patients with bvFTD ( P = .037). The upper extremity was only involved in 1 patient with AD and 1 patient with bvFTD. Sweat results of the 4 recording sites did not differ between both groups. Patients\u2019 history correlated with severe autonomic symptoms as assessed with QSART.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Postganglionic sudomotor involvement in AD and bvFTD is most likely not part of the disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1533317514552319","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T23:31:00Z","timestamp":1412379060000},"page":"400-404","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Peripheral Sympathetic Neuron is Intact in Alzheimer\u2019s Disease and Behavioral Variant of Frontotemporal Dementia"],"prefix":"10.1177","volume":"30","author":[{"given":"Walter","family":"Struhal","sequence":"first","affiliation":[{"name":"Autonomic Unit, Department of Neurology and Psychiatry, Johannes Kepler University, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrija","family":"Javor","sequence":"additional","affiliation":[{"name":"Autonomic Unit, Department of Neurology and Psychiatry, Johannes Kepler University, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Benesch","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics, Vienna Medical University, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milan R.","family":"Vosko","sequence":"additional","affiliation":[{"name":"Autonomic Unit, Department of Neurology and Psychiatry, Johannes Kepler University, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Ransmayr","sequence":"additional","affiliation":[{"name":"Autonomic Unit, Department of Neurology and Psychiatry, Johannes Kepler University, Linz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,10,2]]},"reference":[{"key":"bibr1-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.102343"},{"key":"bibr2-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.08.056"},{"key":"bibr3-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1007\/s102860200009"},{"key":"bibr4-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(93)90233-4"},{"key":"bibr5-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(01)00210-X"},{"key":"bibr6-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(97)01144-2"},{"key":"bibr7-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0901533106"},{"key":"bibr8-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1177\/1533317512459792"},{"key":"bibr9-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-001796"},{"key":"bibr10-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-003-0107-5"},{"key":"bibr11-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-008-0506-8"},{"key":"bibr12-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410140513"},{"key":"bibr13-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1016\/S1566-0702(02)00205-9"},{"key":"bibr14-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.7.939"},{"key":"bibr15-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.6.1546"},{"key":"bibr16-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182120147"},{"key":"bibr17-1533317514552319","volume-title":"Clinical Autonomic Disorders","author":"Low PA","year":"2008","edition":"3"},{"key":"bibr18-1533317514552319","doi-asserted-by":"publisher","DOI":"10.3791\/2502"},{"key":"bibr19-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2004.03.002"},{"key":"bibr20-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.8.1641"},{"key":"bibr21-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199712)20:12<1561::AID-MUS11>3.0.CO;2-3"},{"key":"bibr22-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2008.01086.x"},{"key":"bibr23-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000518"},{"key":"bibr24-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21464"},{"key":"bibr25-1533317514552319","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-0108-y"}],"container-title":["American Journal of Alzheimer's Disease &amp; 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