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This article presents a proposed computer-aided diagnosis (CAD) system for extracting the most effective and significant features of Alzheimer\u2019s disease (AD) using these different discrete transform techniques and MFCC techniques. Linear support vector machine has been used as a classifier in this article. Experimental results conclude that the proposed CAD system using MFCC technique for AD recognition has a great improvement for the system performance with small number of significant extracted features, as compared with the CAD system based on DCT, DST, DWT, and the hybrid combination methods of the different transform techniques.<\/jats:p>","DOI":"10.1177\/1533317515603957","type":"journal-article","created":{"date-parts":[[2015,9,14]],"date-time":"2015-09-14T21:29:23Z","timestamp":1442266163000},"page":"282-293","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Computer-Aided Diagnosis System for Alzheimer\u2019s Disease Using Different Discrete Transform Techniques"],"prefix":"10.1177","volume":"31","author":[{"given":"Mohamed M.","family":"Dessouky","sequence":"first","affiliation":[{"name":"Department of Computer Science and Engineering, Faculty of Electronic Engineering, University of Menoufia, Menoufia, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A.","family":"Elrashidy","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, Faculty of Electronic Engineering, University of Menoufia, Menoufia, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taha E.","family":"Taha","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, Faculty of Electronic Engineering, University of Menoufia, Menoufia, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatem M.","family":"Abdelkader","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering, Faculty of Electronic Engineering, University of Menoufia, Menoufia, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,9,14]]},"reference":[{"key":"bibr1-1533317515603957","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2015.02.003"},{"key":"bibr2-1533317515603957","volume-title":"World Alzheimer Report 2010: The Global Economic Impact of Dementia","author":"Wimo A","year":"2010"},{"key":"bibr3-1533317515603957","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2011.2167628"},{"key":"bibr4-1533317515603957","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200004)47:4<430::AID-ANA5>3.0.CO;2-I"},{"key":"bibr5-1533317515603957","doi-asserted-by":"publisher","DOI":"10.1097\/00002093-199040100-00002"},{"key":"bibr6-1533317515603957","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.64.7.1015"},{"key":"bibr7-1533317515603957","volume-title":"Statistical Parametric Mapping: The Analysis of Functional Brain Images","author":"Friston K","year":"2011"},{"key":"bibr8-1533317515603957","unstructured":"SPM8. 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