{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:00:32Z","timestamp":1777381232283,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We hypothesized that neuropsychological tests could help in identifying preclinical stages of vascular cognitive impairment, when aspirin use might be associated with lower dementia incidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We used data of Canadian Study of Health and Aging (CSHA) which was a longitudinal study of Canadians older than 65 years and was done in 3 waves, 1991 to 1992 (CSHA-1), 1996 to 1997 (CSHA-2), and 2001 to 2002.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>CSHA-1 participants with vascular dementia performed worse in copying pentagons and writing subtests of modified Mini-Mental State Examination test than participants with probable Alzheimer\u2019s disease. Salicylates use was associated with lower incident dementia among normal cognition CSHA-1 participants who had low scores in copying pentagons and writing subtests after controlling for age, sex, education, and vascular risk factors (odds ratio = 0.25, 95% confidence interval: 0.073-0.86, P = .028).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Two simple neuropsychological tests might help in identifying preclinical stages of vascular cognitive impairment, and salicylates use was associated with lower dementia incidence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1533317515619480","type":"journal-article","created":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T21:23:48Z","timestamp":1450992228000},"page":"545-550","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Simple Neuropsychological Tests May Identify Participants in Whom Aspirin Use Is Associated With Lower Dementia Incidence"],"prefix":"10.1177","volume":"31","author":[{"given":"Shahram","family":"Oveisgharan","sequence":"first","affiliation":[{"name":"RUSH Alzheimer\u2019s Disease Center, Rush University Medical Center, Chicago, IL, USA"},{"name":"Neurology Department, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Hachinski","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurological Sciences, University Hospital, University of Western Ontario, London, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,10]]},"reference":[{"key":"bibr1-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-003-0618-y"},{"key":"bibr2-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010178"},{"key":"bibr3-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-001288"},{"key":"bibr4-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39166.597836.BE"},{"key":"bibr5-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000055863.87435.B2"},{"key":"bibr6-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22520"},{"issue":"2","key":"bibr7-1533317515619480","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/ana.22055","volume":"68","author":"Dolan H","year":"2010","journal-title":"Ann Neurol"},{"key":"bibr8-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000237236.88823.47"},{"key":"bibr9-1533317515619480","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1987","edition":"3"},{"key":"bibr10-1533317515619480","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.7.939"},{"key":"bibr11-1533317515619480","volume-title":"Tenth Revision of the International Classification of Diseases","author":"World Health Organization","year":"1987","edition":"10"},{"key":"bibr12-1533317515619480","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994","edition":"4"},{"key":"bibr13-1533317515619480","unstructured":"Canadian Study of Health and Aging: study methods and prevalence of dementia. 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