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Simple linear regression analysis and multiple regression analysis were used to determine the predictors of cognitive decline as measured by the difference in the Mini-Mental State Examination over 1 year. Our sample included 72 patients with AD. Age at the clinic day appointment was 75.3 (standard deviation [SD] = 7.44). History of hypertension and decreased ability to carry out activities of daily living were statistically significant and predicted greater cognitive decline at 1 year. Many previously suggested predictors of cognitive decline were not evidenced in this study. This research helps identify clinically useful predictors of decline in a rural and remote population with AD.<\/jats:p>","DOI":"10.1177\/1533317516662334","type":"journal-article","created":{"date-parts":[[2016,8,29]],"date-time":"2016-08-29T20:07:44Z","timestamp":1472501264000},"page":"643-649","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Predictors of Cognitive Decline in a Rural and Remote Saskatchewan Population With Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"31","author":[{"given":"Drew","family":"Hager","sequence":"first","affiliation":[{"name":"College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Kirk","sequence":"additional","affiliation":[{"name":"Division of Neurology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra G.","family":"Morgan","sequence":"additional","affiliation":[{"name":"Canadian Centre for Health and Safety in Agriculture, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandima","family":"Karunanayake","sequence":"additional","affiliation":[{"name":"Canadian Centre for Health and Safety in Agriculture, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan E.","family":"O\u2019Connell","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,9,24]]},"reference":[{"key":"bibr1-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1159\/000102017"},{"key":"bibr2-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1159\/000144073"},{"key":"bibr3-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5116-4"},{"key":"bibr4-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610211001335"},{"key":"bibr5-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1006\/brcg.1996.0038"},{"key":"bibr6-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1002\/gps.2183"},{"key":"bibr7-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610202008554"},{"key":"bibr8-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1002\/gps.1168"},{"key":"bibr9-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1080\/13607860802154432"},{"key":"bibr10-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1177\/0733464810366564"},{"key":"bibr11-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70178-3"},{"key":"bibr12-1533317516662334","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100009458"},{"issue":"1","key":"bibr13-1533317516662334","first-page":"21","volume":"5","author":"Logsdon RG","year":"1999","journal-title":"J Ment Health Aging"},{"key":"bibr14-1533317516662334","unstructured":"Huba GJ, Melchior LA. 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