{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T10:47:27Z","timestamp":1792320447827,"version":"4.4.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"7-8","license":[{"start":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T00:00:00Z","timestamp":1563235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The most common type of dementia is an Alzheimer\u2019s disease which is a major concern in growing chronic diseases in the geriatric society, and its connection with biochemistry has not been sufficiently understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aims to evaluate the effects of blood biochemistry on Alzheimer\u2019s disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>\n                      Eight participants aged 55+ with Alzheimer\u2019s disease were analyzed. A cross-sectional work has conducted. Eighty patients have been divided into 2 groups as group A and group B according to laboratory findings including glycosylated hemoglobin, high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (TC), triglycerides (TGA), vitamin D, folic acid, and vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      . Mean Mini-Mental State Examination scores between these different 2 groups have been compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>High levels of HDL, vitamin D, and folic acid correlate with cognitive scores, whereas high levels of total cholesterol, HbA1c, LDL show a negative effect on cognition scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>High-density lipoprotein, vitamin D, folic acid, cholesterol, HgA1c, and LDL have an effect on dementia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1533317519862108","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T23:16:15Z","timestamp":1563318975000},"page":"464-468","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Investigation of the Effects of Biochemical Parameters on Alzheimer\u2019s Disease"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4996-7370","authenticated-orcid":false,"given":"Mustafa","family":"Gokce","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Faculty of Pharmacy, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed Yunus","family":"Bektay","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy, Faculty of Pharmacy, Bezmialem Vak\u0131f University, Fatih, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabia","family":"Selvitop","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Toprak","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Medical Informatics, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulsen Babacan","family":"Yildiz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,7,16]]},"reference":[{"key":"bibr1-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0909142"},{"key":"bibr2-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1007\/BF00294425"},{"key":"bibr3-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.005"},{"key":"bibr4-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(97)00056-0"},{"key":"bibr5-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-8610(04)70399-0"},{"key":"bibr6-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2015.240515"},{"key":"bibr7-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12637"},{"key":"bibr8-1533317519862108","doi-asserted-by":"publisher","DOI":"10.2337\/db14-0287"},{"key":"bibr9-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0b013e3182299496"},{"key":"bibr10-1533317519862108","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003430"},{"key":"bibr11-1533317519862108","unstructured":"Arseneau E. 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