{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T20:44:42Z","timestamp":1789764282294,"version":"4.0.1"},"reference-count":38,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Alzheimers Dis Other Demen"],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The study aims at identifying features predictive of early onset of dementia in Parkinson\u2019s disease (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>103 non-demented PD patients were evaluated on various scales at baseline and 89 patients at 3-year follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>By the end of the study 43.8% of patients developed dementia. The development of dementia was linked to the baseline Mini Mental State Examination score (Pearson coefficient r = .404, p = 0.013), the presence of autonomic dysfunctions (r = \u2212.621, p &lt; 0.001) and insomnia (r = \u2212.526, p = 0.001). A binary logistic regression analysis showed that the development of dementia was correlated strongly with the presence of autonomic dysfunctions (95% CI 2.60 to 52.83, p &lt; 0.001), and insomnia (95% CI 0.60 to 0.95, p = 0.017).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Patients with signs of autonomic dysfunction and insomnia are at higher risk for developing dementia and deserve closer monitoring of cognitive symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15333175211021369","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T05:33:21Z","timestamp":1622612001000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical Markers May Identify Patients at Risk for Early Parkinson\u2019s Disease Dementia: A Prospective Study"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0793-2877","authenticated-orcid":false,"given":"Anamaria","family":"Jurcau","sequence":"first","affiliation":[{"name":"Neurology ward, Clinical Municipal Hospital \u201cdr. G Curteanu\u201d Oradea, Oradea, Romania"},{"name":"Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vharoon Sharma","family":"Nunkoo","sequence":"additional","affiliation":[{"name":"Neurology ward, Clinical Municipal Hospital \u201cdr. 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