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This study evaluated clinical events, healthcare utilization, and healthcare costs of patients with DLB vs other dementia types with psychosis (ODP). Study patients included commercial and Medicare Advantage with Part D enrollees aged \u226540\u00a0years with evidence of DLB and ODP from 6\/01\/2015\u20125\/31\/2019. Compared with patients with ODP, more patients with DLB had clinical events including anticholinergic effects, neurologic effects, and cognitive decline. Patients with DLB used more healthcare resources with greater dementia-related office and outpatient visits and psychosis-related inpatient stays and office, outpatient, and emergency visits compared with their ODP patient counterparts. Patients with DLB also incurred higher healthcare costs for all-cause and dementia-related office visits and pharmacy fills, and psychosis-related total costs. Understanding the clinical and economic impact of DLB and ODP is important to improve care for patients with dementia.<\/jats:p>","DOI":"10.1177\/15333175231163521","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T18:38:16Z","timestamp":1678387096000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Burden of Illness Among Patients with Psychosis due to Dementia with Lewy Bodies and Other Dementias"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4125-9310","authenticated-orcid":false,"given":"Monica","family":"Frazer","sequence":"first","affiliation":[{"name":"Optum Inc., Eden Prairie, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4227-1234","authenticated-orcid":false,"given":"Nazia","family":"Rashid","sequence":"additional","affiliation":[{"name":"Acadia Pharmaceuticals, San Diego, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Bunner","sequence":"additional","affiliation":[{"name":"Optum Inc., Eden Prairie, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Skoog","sequence":"additional","affiliation":[{"name":"Acadia Pharmaceuticals, San Diego, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Abler","sequence":"additional","affiliation":[{"name":"Acadia Pharmaceuticals, San Diego, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"bibr1-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/gbx169"},{"key":"bibr2-15333175231163521","volume-title":"World Alzheimer Report 2010: The Global Economic Impact of Dementia","author":"Wimo APM","year":"2010"},{"key":"bibr3-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1204629"},{"key":"bibr4-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.1.62"},{"key":"bibr5-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2004.52054.x"},{"key":"bibr6-15333175231163521","volume-title":"Alzheimer's Disease and Chronic Health Conditions: The Real Challenge for 21st Century Medicine","author":"Association A","year":"2020"},{"key":"bibr7-15333175231163521","volume-title":"Practical Dementia Care","author":"Rabins PVLC","year":"1999"},{"key":"bibr8-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.12.1475"},{"key":"bibr9-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.5.708"},{"key":"bibr10-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.9.4.556"},{"key":"bibr11-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540340040030"},{"key":"bibr12-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(200002)15:2<181::AID-GPS96>3.0.CO;2-I"},{"key":"bibr13-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.147.8.1049"},{"key":"bibr14-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(199909)14:9<701::AID-GPS5>3.0.CO;2-#"},{"key":"bibr15-15333175231163521","first-page":"253","volume":"5","author":"Cummings J","year":"2018","journal-title":"J Prev Alzheimers Dis"},{"key":"bibr16-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1177\/089198870201500402"},{"key":"bibr17-15333175231163521","volume-title":"Dementia","author":"Mckeith I","year":"2017"},{"key":"bibr18-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12068"},{"key":"bibr19-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.2.351"},{"key":"bibr20-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-010357"},{"key":"bibr21-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)03399-7"},{"key":"bibr22-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1177\/1533317506297517"},{"key":"bibr23-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.305.6855.673"},{"key":"bibr24-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(199906)14:6<459::AID-GPS957>3.0.CO;2-R"},{"key":"bibr25-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0b013e3181e6a4d7"},{"key":"bibr26-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1370\/afm.1364"},{"key":"bibr27-15333175231163521","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq433"},{"key":"bibr28-15333175231163521","volume-title":"HCUP CCS [computer Program]","year":"2015"},{"key":"bibr29-15333175231163521","volume-title":"Consumer Price Index. 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