{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T09:15:08Z","timestamp":1777713308450,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T00:00:00Z","timestamp":1424131200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:p>Prolidase deficiency (PD) is a rare autosomal recessive disorder that has symptoms such as skin ulcers, characteristic facies, mental retardation, skeletal deformities, hematological anomalies, splenomegaly, and chronic infections. Deficiency of prolidase leads to the increased excretion of proline in urine, which causes impaired collagen synthesis and delay in wound healing. This case reports a 40-year-old female who has had cutaneous ulcers since the age of 7 years. We also recognized borderline intellectual functioning as well as hematologic abnormalities and splenomegaly. We present this rare case to draw attention to consider prolidase deficiency in the differential diagnosis of leg ulcers.<\/jats:p>","DOI":"10.1177\/1534734615570360","type":"journal-article","created":{"date-parts":[[2015,2,18]],"date-time":"2015-02-18T01:49:00Z","timestamp":1424224140000},"page":"92-94","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["A Case of Prolidase Deficiency Accompanying Leg Ulcers"],"prefix":"10.1177","volume":"14","author":[{"given":"Berna","family":"Solak","sequence":"first","affiliation":[{"name":"Sakarya University, School of Medicine, Sakarya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabia Oztas","family":"Kara","sequence":"additional","affiliation":[{"name":"Sakarya University Training and Research Hospital, Sakarya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teoman","family":"Erdem","sequence":"additional","affiliation":[{"name":"Sakarya University, School of Medicine, Sakarya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuba","family":"Muftuoglu","sequence":"additional","affiliation":[{"name":"Haydarpasa Hospital of G\u00fclhane Military Medical Academy, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,2,17]]},"reference":[{"key":"bibr1-1534734615570360","doi-asserted-by":"publisher","DOI":"10.1097\/00129334-200411000-00011"},{"key":"bibr2-1534734615570360","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.03157.x"},{"key":"bibr3-1534734615570360","doi-asserted-by":"publisher","DOI":"10.1136\/adc.76.5.441"},{"key":"bibr4-1534734615570360","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.2008.00485.x"},{"key":"bibr5-1534734615570360","first-page":"12","volume":"32","author":"Ozcan O","year":"2007","journal-title":"Turk J Biochem"},{"key":"bibr6-1534734615570360","first-page":"759","volume":"113","author":"Jackson SH","year":"1975","journal-title":"Can Med Assoc J"},{"key":"bibr7-1534734615570360","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.1996.tb01191.x"},{"key":"bibr8-1534734615570360","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2000.01760.x"},{"key":"bibr9-1534734615570360","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.04998.x"}],"container-title":["The International Journal of Lower Extremity Wounds"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1534734615570360","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1534734615570360","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1534734615570360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:07:54Z","timestamp":1777457274000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1534734615570360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,17]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1177\/1534734615570360"],"URL":"https:\/\/doi.org\/10.1177\/1534734615570360","relation":{},"ISSN":["1534-7346","1552-6941"],"issn-type":[{"value":"1534-7346","type":"print"},{"value":"1552-6941","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,17]]}}}