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Primary cutaneous infections are uncommon, but they are typically severe and are associated with significant morbidity and mortality. The pathogenetic factors leading to S. marcescens infection are not fully understood, but contributing virulence factors include proteases, secreted exotoxins, and the formation of biofilm. We report a case of cellulitis occurring in a splenectomized patient, which led to multiple wound debridements and a transmetatarsal amputation. This dramatic case led us to review the published literature on soft tissue infections caused by S. marcescens.<\/jats:p>","DOI":"10.1177\/1534734616636271","type":"journal-article","created":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T20:24:21Z","timestamp":1460665461000},"page":"161-168","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["<i>Serratia marcescens<\/i>\n                    Bullous Cellulitis in a Splenectomized Patient"],"prefix":"10.1177","volume":"15","author":[{"given":"John B.","family":"Fournier","sequence":"first","affiliation":[{"name":"Department of Dermatology, Roger Williams Medical Center, Providence, RI, USA"},{"name":"Department of Dermatology, Boston University School of Medicine, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganary","family":"Dabiri","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Roger 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