{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:04:49Z","timestamp":1789085089664,"version":"build-2803163510"},"reference-count":30,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:p>The purpose of this study is to investigate the outcomes of diabetic individuals with ischemic heel ulcers. The study group was composed of a consecutive sample of persons with diabetic ischemic foot ulcers managed by a preset multidisciplinary limb salvage protocol, including revascularization through endovascular technique. The outcome measures were healing, major amputation (above the ankle), and death at 1-year of follow-up. The outcomes between patients with heel ulcers (HUs) and without (NHUs) were compared. A total of 254 patients were recruited. There were 50\/254 (19.7%) HUs and 204\/254 (79.3%) NHUs. Overall, 190\/254 (74.8%) patients healed. The rate of healing for HUs and NHUs was 30\/50 (60%) and 160\/204 (78.4%); P = .03, respectively. Major amputation occurred in 24\/254 (9.4%) patients. The rates of major amputation for HUs and NHUs were 10\/50 (20%) and 14\/204 (6.9%; P = .002), respectively; 40\/254 (15.7%) patients died, unhealed. The rates of mortality for HUs and NHUs were 10\/50 (20%) and 30\/204 (14.7%; P = .07), respectively. In HUs patients, absence of infection [95% CI = 3.1 (1.6-5.5); P = .002] and superficial ulcers [95% CI = 4.4 (2.2-9.3); P = .0001] were independent predictors of healing, whereas revascularization failure [95% CI = 8.1 (1.5.0-19.4); P = .0001], involvement of the plantar arch [95% CI = 6.3 (2.0-15.4); P = .0001], and dialysis [95% CI = 2.2 (1.3-4.5); P = .006] were independent predictors of major amputation. A multidisciplinary approach achieves good rate of limb salvage in people with diabetic ischemic heel ulcers.<\/jats:p>","DOI":"10.1177\/1534734619884438","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T04:32:16Z","timestamp":1574224336000},"page":"275-281","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Limb Salvage in Diabetic Patients With Ischemic Heel Ulcers"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3789-9622","authenticated-orcid":false,"given":"Marco","family":"Meloni","sequence":"first","affiliation":[{"name":"University of Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Izzo","sequence":"additional","affiliation":[{"name":"University of Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Giurato","sequence":"additional","affiliation":[{"name":"University of Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Brocco","sequence":"additional","affiliation":[{"name":"Abano Terme Polyclinic, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Gandini","sequence":"additional","affiliation":[{"name":"University of Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Uccioli","sequence":"additional","affiliation":[{"name":"University of Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"bibr1-1534734619884438","unstructured":"International Working Group on the Diabetic Foot. 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