{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:24:55Z","timestamp":1791469495818,"version":"4.3.4"},"reference-count":44,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>This review discusses the evidence on diabetic retinopathy (DR) in patients with diabetic foot ulceration (DFU). A systematic literature review was performed on PubMed, Medline, Springer Nature, and Scopus, following the PRISMA guidelines, using the following terms, individually or in combination: \u201cdiabetic foot ulcer\u201d OR \u201cdiabetic foot syndrome\u201d OR \u201cDFU\u201d and \u201cdiabetic retinopathy.\u201d The initial search yielded 648 articles published between 1975 and 2020. After applying exclusion and inclusion criteria, a total of 9 articles were analyzed, assessing the correlations between DR and DFU. In all cases, DR and especially proliferative diabetic retinopathy were significantly higher in the presence of DFU, though the frequency of DR showed large variability (22.5% to 95.6%). There was a significant correlation between advanced stages of DFU and increased frequency of DR and proliferative diabetic retinopathy. On the other hand, there is a risk of accelerated progression of DR in nonhealing DFUs, possibly related to chronic inflammation and associated infection. Hence, patients with DFUs should be monitored by an ophthalmologist, and those with DR should be promptly referred to a specialized diabetic foot clinic.<\/jats:p>","DOI":"10.1177\/1534734620982237","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T23:45:47Z","timestamp":1608680747000},"page":"98-103","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Diabetic Retinopathy in Patients With Diabetic Foot Ulcer: A Systematic Review"],"prefix":"10.1177","volume":"20","author":[{"given":"Dragos","family":"Serban","sequence":"first","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, Bucharest, Romania"},{"name":"Emergency University Hospital Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7320-785X","authenticated-orcid":false,"given":"Nikolaos","family":"Papanas","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace, Alexandroupolis, Greece"},{"name":"University Hospital of Alexandroupolis, Alexandroupolis, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7474-2395","authenticated-orcid":false,"given":"Ana Maria","family":"Dascalu","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, Bucharest, Romania"},{"name":"Emergency University Hospital Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Stana","sequence":"additional","affiliation":[{"name":"Emergency University Hospital Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Andrada","family":"Nicolae","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, Bucharest, Romania"},{"name":"Emergency University Hospital Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geta","family":"Vancea","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristinel Dumitru","family":"Badiu","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denisa","family":"Tanasescu","sequence":"additional","affiliation":[{"name":"\u201cLucian Blaga\u201d University Sibiu, Sibiu, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corneliu","family":"Tudor","sequence":"additional","affiliation":[{"name":"Emergency University Hospital Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona Andreea","family":"Balasescu","sequence":"additional","affiliation":[{"name":"Emergency University Hospital Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Pantea-Stoian","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila\u201d Bucharest, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"bibr1-1534734620982237","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00618-8"},{"key":"bibr2-1534734620982237","doi-asserted-by":"publisher","DOI":"10.1177\/1534734619853657"},{"key":"bibr3-1534734620982237","doi-asserted-by":"publisher","DOI":"10.1177\/1534734611400255"},{"key":"bibr4-1534734620982237","doi-asserted-by":"publisher","DOI":"10.1001\/archfami.5.7.391"},{"key":"bibr5-1534734620982237","doi-asserted-by":"crossref","unstructured":"Zafar S, Rahim K, Khan IU, Yasin M, Dawood M, Saleha S. 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