{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:44:11Z","timestamp":1791312251078,"version":"4.3.1"},"reference-count":10,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T00:00:00Z","timestamp":1697068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>\n                    We hypothesized that foot infections secondary to a puncture wounds (PWs) have a worse prognosis concerning infection-related mortality, recurrence of the infection, and healing than those secondary to a chronic ulcer. We conducted a prospective study consisting of 200 patients with moderate-to-severe diabetic foot infections. The cohort consisted of 155 men (77.5%) and 45 women (22.5%). The mean age of the patients was 59 years (standard deviation 12.2). Puncture wounds were the cause of the infection in 107 patients (53.5%) and a chronic ulcer was the cause in 93 patients (46.5%). One hundred and eleven patients (55.5%) had moderate and 89 (44.5%) had severe infections. Osteomyelitis was more frequently found in chronic ulcers (71%) than in PWs (44.9%),\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001. Cox's survival analysis using PWs as an explanatory variable showed no association with infection-related mortality (hazard ratio [HR] 1.06, 95% confidence interval [CI] 0.32-3.46,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.92), time to recurrence of infection (HR 0.64, 95% CI 0.27-1.51,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.30), and time to healing (HR 0.81, 95% CI 0.60-1.08,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.15). More than half of our patients had PWs as the mechanism by which the infection occurred. These patients usually had a lower rate of osteomyelitis but required hospitalization and antibiotic therapy more frequently than patients with infected chronic ulcers. We found no difference in outcomes between the 2 groups.\n                  <\/jats:p>","DOI":"10.1177\/15347346231207437","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T03:36:25Z","timestamp":1697081785000},"page":"271-275","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Differences in Foot Infections Secondary to Puncture Wounds or Chronic Ulcers in Diabetes"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0028-765X","authenticated-orcid":false,"given":"Gerardo","family":"V\u00edquez-Molina","sequence":"first","affiliation":[{"name":"Diabetic Foot Unit, San Juan de Dios Hospital, San Jos\u00e9 de Costa Rica, Costa Rica"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Arag\u00f3n-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Department of Surgery, Diabetic Foot Unit, La Paloma Hospital, Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9530-9729","authenticated-orcid":false,"given":"Mar\u00eda Eugenia","family":"L\u00f3pez-Valverde","sequence":"additional","affiliation":[{"name":"Endocrinology and Nutrition Service, Juan Ram\u00f3n Jimenez Hospital, Huelva, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Arag\u00f3n-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Surgery, Diabetic Foot Unit, La Paloma Hospital, Las Palmas de Gran Canaria, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Arag\u00f3n-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Geriatrics Service, Getafe University Hospital, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"Rojas-Bonilla","sequence":"additional","affiliation":[{"name":"Diabetic Foot Unit, San Juan de Dios Hospital, San Jos\u00e9 de Costa Rica, Costa Rica"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,10,12]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jfas.2019.08.013"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2482-11-27"},{"issue":"2","key":"e_1_3_2_4_2","first-page":"692","article-title":"Is walking barefoot a risk factor for diabetic foot disease in developing countries?","volume":"7","author":"Jayasinghe SA","year":"2007","unstructured":"Jayasinghe SA, Atukorala I, Gunethilleke B, Siriwardena V, Herath SC, De Abrew K. Is walking barefoot a risk factor for diabetic foot disease in developing countries? Rural Remote Health. 2007;7(2):692.","journal-title":"Rural Remote Health"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(96)00283-5"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.7547\/87507315-87-7-321"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3280"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa161"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-022-00957-0"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14017"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz489"}],"container-title":["The International Journal of Lower Extremity Wounds"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15347346231207437","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15347346231207437","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15347346231207437","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T21:47:11Z","timestamp":1779400031000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15347346231207437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,12]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1177\/15347346231207437"],"URL":"https:\/\/doi.org\/10.1177\/15347346231207437","relation":{},"ISSN":["1534-7346","1552-6941"],"issn-type":[{"value":"1534-7346","type":"print"},{"value":"1552-6941","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,12]]}}}