{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T09:02:55Z","timestamp":1777712575923,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>\n                    Patients with diabetic foot ulcer (DFU) are prone to major complications including amputations. Traditional remedies (TR) have been used to treat DFU around the world. This study aims to identify the prevalence of TR among patients with DFU in our local cohort and its effect on DFU. 1408 patients were included in the analysis. Data were collected retrospectively from patients\u2019 medical records. DFU characteristics include grading ulcers using the Wagner scale (WG) and infections (cellulitis and osteomyelitis). Ulcer management (UM) includes medical treatment, self-medical treatment, traditional treatment, and medical-traditional treatment. The mean age of the cohort was 60 years (SD\u2009=\u200912.4). The mean duration of diabetes was 18.6 years (SD\u2009=\u20099.3) and the mean duration of open wounds was 206.9 days (SD\u2009=\u2009545.6). The majority were males (71%) and had type 2 diabetes (96%, SD\u2009=\u2009.204). Forty-three percent of patients were treated with TR (29% were self-prescribed and 14% prescribed by a physician) while 48% had medical treatment and 10% were self-treated using medical treatment. More than two-thirds of the cohort had cellulitis and\/or osteomyelitis at the time of presentation. The use of traditional treatment was significantly associated with higher WG (WG 4 OR = \u20091.936, 95% CI: 1.338-2.800; WG 5 OR = \u20092.937, 95% CI:1.614-5.346;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u20090.05). Moreover, osteomyelitis was associated with medical-traditional treatment (OR = 1.608, 95% CI: 1.006-2.572;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u20090.05) and increased wound depth (WG 3 OR = \u20091.969, 95% CI: 1.193-3.250; WG 4 OR = \u20091.874, 95% CI: 1.115-3.15;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u20090.05). There is high use of TR for the treatment of DFU in our cohort. High Wagner-grade of foot ulcers and the presence of osteomyelitis were highly associated with DFU. This study showed for the first time the use of traditional potions by medical physicians. Both physicians and patients need to be made aware of the detrimental effects of using traditional methods on DFU.\n                  <\/jats:p>","DOI":"10.1177\/15347346231211372","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T02:38:16Z","timestamp":1699324696000},"page":"205-212","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of Traditional Remedies for Treatment of Diabetic Foot Ulcers: A Cross-Sectional Study at a Tertiary Center in Saudi Arabia"],"prefix":"10.1177","volume":"25","author":[{"given":"Khalid M.","family":"Edrees","sequence":"first","affiliation":[{"name":"Research Department, Dr Khalid Edrees Medical Center, Jeddah, Makkah, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2733-5453","authenticated-orcid":false,"given":"Alanood I.","family":"Alqahtani","sequence":"additional","affiliation":[{"name":"Research Department, Dr Khalid Edrees Medical Center, Jeddah, Makkah, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maram T.","family":"Alkhatieb","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine, King Abdelaziz University, Jeddah, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,11,6]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1289\/EHP.01109S169"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4314\/AJTCAM.V8I3.65276"},{"key":"e_1_3_2_4_2","unstructured":"World Health Organization. Programme on Traditional Medicine. (2002). WHO Traditional Medicine Strategy 2002-2005; 2002. https:\/\/apps.who.int\/iris\/handle\/10665\/67163. Accessed March 5 2023."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.DIABRES.2019.107843"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1520-7560(200009\/10)16:1+<::AID-DMRR113>3.0.CO;2-S"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/JAMA.293.2.217"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/2005935"},{"issue":"6","key":"e_1_3_2_9_2","first-page":"659","article-title":"Scorpion puncture: Medical treatment and home remedies","volume":"47","author":"Lagunas-Flores A","year":"2009","unstructured":"Lagunas-Flores A, Lagunas-Jaimes GN. Scorpion puncture: Medical treatment and home remedies. Rev Med Inst Mex Seguro Soc. 2009;47(6):659\u2010664. http:\/\/PMID: 20602906. Accessed April 10, 2023.","journal-title":"Rev Med Inst Mex Seguro Soc"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/S12906-022-03564-7"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2022.e08873"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/IJERPH16040559"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/107110078100200202\/ASSET\/107110078100200202.FP.PNG_V03"},{"key":"e_1_3_2_14_2","unstructured":"Brown Brandon D Hood WKL. Cellulitis. StatPearls Internet. Published online 2022. PMID: 31747177. Accessed June 25 2023."},{"issue":"6","key":"e_1_3_2_15_2","first-page":"486","article-title":"A review on botanicals with wound healing activity for Pemphigus vulgaris: Perspective of traditional Persian medicine and conventional medicine","volume":"7","author":"Atarzadeh F","year":"2017","unstructured":"Atarzadeh F, Jaladat AM, Daneshfard B, Dastgheib L, Kamalinejad M, Amin G. A review on botanicals with wound healing activity for Pemphigus vulgaris: Perspective of traditional Persian medicine and conventional medicine. Avicenna J Phytomed. 2017;7(6):486. \/pmc\/articles\/PMC5745532\/. Accessed April 16, 2023.","journal-title":"Avicenna J Phytomed"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/136932"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.JEP.2017.08.003"},{"issue":"11","key":"e_1_3_2_18_2","first-page":"2065","article-title":"Is cinnamon efficacious for glycaemic control in type-2 diabetes mellitus?","volume":"70","author":"Sharma S","year":"2020","unstructured":"Sharma S, Mandal A, Kant R, Jachak S, Jagzape M. Is cinnamon efficacious for glycaemic control in type-2 diabetes mellitus? J Pak Med Assoc. 2020;70(11):2065\u20102069. https:\/\/pubmed.ncbi.nlm.nih.gov\/33341863\/. 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