{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:48:54Z","timestamp":1790016534234,"version":"4.0.1"},"reference-count":34,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:00:00Z","timestamp":1709164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Diabetic foot ulcer is a serious and common complication of diabetes that often leads to significant morbidity and even amputation if not properly treated. Current treatment options, such as wound dressing, have limitations in promoting efficient healing. There is a need for effective interventions that can expedite the healing process and enhance the time required for complete healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>This prospective single-blinded randomized control trial studied diabetic mellitus type 2 patients with ulcer in their second-degree feet from February 2019 to February 2023 in the Diabetic Foot Center, King Fahad Specialist Hospital Al Qassim-KSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      This study involved 120 patients with a mean age of 59.64\u2009\u00b1\u200910.21. And 63% to 52.5% of them were males and 57% to 47.5% were females. The mean healing time was about 12.76\u2009\u00b1\u20094.08 days. Cases were divided into 4 equal groups with altered treatment procedures: honey alone, hydrogel alone, honey, and hydrogel combination alternately (3 intervention groups), and fucidin ointment or cream alone (1 control group), with 30 participants in each group. We revealed that the mean healing times for honey alone, hydrogel alone, and honey and hydrogel alternately were 12.20, 13.97, and 10.83 days, respectively. While it was 14.03 days in the control Fucidin ointment or cream [significantly\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.04)].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>From the findings of the present study, we noticed that faster healing time among diabetic foot cases could be accomplished by treatment with a combination of honey and hydrogel alternately. Therefore, this therapy is effective in reducing the risk of diabetic foot ulcers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15347346241233236","type":"journal-article","created":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T02:47:32Z","timestamp":1709261252000},"page":"496-502","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["The Influence of Honey and Hydrogel Products Therapy on Healing Time in Diabetic Foot"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5621-5877","authenticated-orcid":false,"given":"Wael Mahmoud","family":"Searan","sequence":"first","affiliation":[{"name":"Diabetic Foot Center, Center Diabetes &amp; Endocrinology, KFSH, Buraidha Al-Qassim, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed A.","family":"Abdalqader","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Cyberjay, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Husni Ahmed","family":"Al-Goshae","sequence":"additional","affiliation":[{"name":"OD Science University (MSU), Shahalam, Malaysia"},{"name":"Dandee University, Nethergate, Dundee, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamdan Mohammed","family":"Nor","sequence":"additional","affiliation":[{"name":"Oxford University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamad Saleh","family":"Al-Shubrumi","sequence":"additional","affiliation":[{"name":"Diabetes and Endocrinology Center, Buraidha Al-Qassim, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hani","family":"Badahdah","sequence":"additional","affiliation":[{"name":"Dr Edrees Specialized Medical Center, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.109119"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/app11115159"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v6.i1.37"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2016.1231932"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2020.04.004"},{"issue":"10","key":"e_1_3_2_7_2","first-page":"721","article-title":"A randomized, controlled clinical trial of honey-impregnated dressing for treating diabetic foot ulcer","volume":"25","author":"Imran M","year":"2015","unstructured":"Imran M, Hussain MB, Baig M. 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