{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:09:07Z","timestamp":1792789747476,"version":"4.5.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T00:00:00Z","timestamp":1721520000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100004911","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Piau\u00ed","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004911","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    Diabetic foot ulcers (DFUs) result in tissue damage or impairment of deeper structures that affect quality of life. The impacts are numerous, and even after a long treatment period, 65% of patients experience recurrence. Among the interventions used to accelerate the healing process of DFUs, photobiomodulation therapy (PBMT) is a painless, noninvasive, and low-cost treatment. To achieve effective therapeutic results optimal PBMT parameters are necessary. The positive effect of PBMT on diabetic cells may be dependent on fluence (J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    ) and wavelength (nm). This double-blind, randomized clinical trial will be conducted at the University Clinic of Physical Therapy. One hundred patients will be randomly placed in 4 groups. A Laserpulse Ibramed (Helium-Neon, HeNe, 660 nm) with 20\u2005W power will be used (continuous mode), with doses stipulated for each treatment group (GL1, 4\u2005J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    ; GL2, 8\u2005J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    ; GL3, 12\u2005J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    ) and Endophoton KLD GaAs 904 nm (ST, 10\u2005J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    ) for 2 nonconsecutive days per week for 10 weeks, for a total of 20 sessions. The primary outcomes will be ulcer healing rate and University of Texas classification scores. Patients\u2019 DFUs will be assessed on the 1st day, 5 weeks, and 10 weeks of treatment then 1 month after the end of treatment. This study may aid effective clinical decision-making for the management of DFUs.\n                  <\/jats:p>","DOI":"10.1177\/15347346241266732","type":"journal-article","created":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T05:42:47Z","timestamp":1721540567000},"page":"712-717","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of Using Photobiomodulation (660 Nanometers) for the Treatment of Diabetic Ulcers: Protocol for a Randomized Controlled Trial"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2985-9840","authenticated-orcid":false,"given":"Mariana Bezerra","family":"Miranda","sequence":"first","affiliation":[{"name":"Integrated Center for Medical Specialties, Parna\u00edba, PI, Brazil"},{"name":"Universidade Federal do Delta do Parna\u00edba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8495-9910","authenticated-orcid":false,"given":"Rebeca","family":"Barbosa da Rocha","sequence":"additional","affiliation":[{"name":"Integrated Center for Medical Specialties, Parna\u00edba, PI, Brazil"},{"name":"Universidade Federal do Delta do Parna\u00edba"},{"name":"Department of Physical Therapy, Federal University of Delta do Parna\u00edba, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayana Fontenele","family":"Alves","sequence":"additional","affiliation":[{"name":"Integrated Center for Medical Specialties, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinicius Saura","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Integrated Center for Medical Specialties, Parna\u00edba, PI, Brazil"},{"name":"Universidade Federal do Delta do Parna\u00edba"},{"name":"Department of Physical Therapy, Federal University of Delta do Parna\u00edba, Parna\u00edba, PI, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,7,21]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2019.107843"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13047-020-00383-2"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13054"},{"issue":"5","key":"e_1_3_3_5_2","first-page":"1103","article-title":"Hyperglycaemic conditions decrease cultured keratinocyte mobility: implications for impaired wound healing in patients with diabetes","volume":"159","author":"Lan CC","year":"2008","unstructured":"Lan CC, Liu IH, Fang AH, Wen CH, Wu CS. 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