{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:59:47Z","timestamp":1777712387586,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T00:00:00Z","timestamp":1775260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The International Journal of Lower Extremity Wounds"],"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare the modifications in foot structure and shape in obese patients with or without type 2 diabetes mellitus (T2DM) after weight loss.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We studied all patients submitted to bariatric surgery in our Department between January and March 2019 with body mass index (BMI) between 40 and 48\u2005kg\/m2 before and after the weight loss, dividing them into two groups according to presence (Group 1) or absence (Group 2) of T2DM. We compared changes in: skin temperature at first and fifth metatarsal joint (MJ), ultrasound skin, subcutaneous and fascia thickness, dorsal and ankle circumferences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We enrolled 46 patients: 19 in Group 1 (M\/F 11\/8; mean age 48.2\u2009\u00b1\u200910.3 yrs) and 27 in Group 2 (M\/F 10\/17, mean age 46.8\u2009\u00b1\u200910.0). Time requested for expected weight loss was longer in Group 1 (461.5\u2009\u00b1\u2009131.3 days vs 334.2\u2009\u00b1\u2009106.4,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.0011). Foot and leg dimensions were decreased in both groups, but reduction was greater in Group 2. Also the reduction of skin temperature was greater in Group 2 both at first and at fifth MJ (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.03 and .02). On the contrary ultrasound skin and subcutaneous thickness reduction was significantly greater in Group 1 both dorsally (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.009) and plantarly (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.05) as well as fascia thickness (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our data confirm structural body changes induced by weight loss in severely obese patients, with different patterns in patients affected or not from T2DM: a more important decrease in tissue thickness in the former and a greater volume reduction in the latter, probably related to different oedema resorption.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Level of evidence:<\/jats:bold>\n                      Clinical research.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15347346261429745","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T07:27:01Z","timestamp":1775287621000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Different Foot Structural Changes Pattern Between Diabetic and not Diabetic Patients After Weight Loss Due to Bariatric Surgery in Severe Obesity"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9007-9378","authenticated-orcid":false,"given":"Elisabetta","family":"Iacopi","sequence":"first","affiliation":[{"name":"University of Pisa (I), Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Riitano","sequence":"additional","affiliation":[{"name":"University of Pisa (I), Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Giangreco","sequence":"additional","affiliation":[{"name":"University of Pisa (I), Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario","family":"Bellini","sequence":"additional","affiliation":[{"name":"University of Pisa (I), Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Tramonti","sequence":"additional","affiliation":[{"name":"University of Pisa (I), Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmelo","family":"Chisari","sequence":"additional","affiliation":[{"name":"University of Pisa (I), Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Piaggesi","sequence":"additional","affiliation":[{"name":"University of Pisa (I), Pisa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,4]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00399096"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.12.004"},{"key":"e_1_3_2_4_2","unstructured":"Downloaded from https:\/\/idf.org\/about-diabetes\/diabetes-facts-figures\/ on October 2023 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