{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T04:37:27Z","timestamp":1792816647204,"version":"4.5.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T00:00:00Z","timestamp":1466553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Korean Ministry of Health & Welfare","award":["CIMI-14-01-23"],"award-info":[{"award-number":["CIMI-14-01-23"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Integr Cancer Ther"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p>Objective. The aim of this study was to determine the feasibility, acceptability, and safety of using moxibustion for treating anorexia and improving quality of life in patients with metastatic cancer. Methods. We conducted a randomized sham-controlled trial of moxibustion. Sixteen patients with metastatic cancer were recruited from Daejeon, South Korea. The patients were randomly placed into a true or a sham moxibustion group and received 10 true or sham moxibustion treatments administered to the abdomen (CV12, CV8, CV4) and legs (ST36) over a 2-week period. Outcome measures included interest in participating in the trial, identification of successful recruitment strategies, the appropriateness of eligibility criteria, and compliance with the treatment plan (ie, attendance at treatment sessions). Clinical outcomes included results of the Functional Assessment of Anorexia\/Cachexia Therapy (FAACT), answers on the European Organization for Research and Treatment of Cancer 30-item core quality of life (EORTC QLQ-C30) questionnaires, scores on the visual analogue scale (VAS), and the results from blood tests and a safety evaluation. Results. Moxibustion was an acceptable intervention in patients with metastatic cancer. Compliance with the treatment protocol was high, with 11 patients completing all 10 treatments. No serious adverse events related to moxibustion occurred, but 4 patients in the true moxibustion group reported mild rubefaction, which disappeared in a few hours. Conclusion. This study suggests that moxibustion may be safely used to treat anorexia and improve quality of life in patients with metastatic cancer. However, further research is needed to confirm this result.<\/jats:p>","DOI":"10.1177\/1534735416654762","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T22:03:04Z","timestamp":1466632984000},"page":"118-125","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["A Feasibility Study of Moxibustion for Treating Anorexia and Improving Quality of Life in Patients With Metastatic Cancer: A Randomized Sham-Controlled Trial"],"prefix":"10.1177","volume":"16","author":[{"given":"Ju-Hyun","family":"Jeon","sequence":"first","affiliation":[{"name":"Daejeon Korean Medicine Hospital of Daejeon University, Daejeon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong-Kwan","family":"Cho","sequence":"additional","affiliation":[{"name":"Dunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So-Jung","family":"Park","sequence":"additional","affiliation":[{"name":"Dunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwi-Joong","family":"Kang","sequence":"additional","affiliation":[{"name":"Dunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyungmin","family":"Kim","sequence":"additional","affiliation":[{"name":"Daejeon Korean Medicine Hospital of Daejeon University, Daejeon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In-Chul","family":"Jung","sequence":"additional","affiliation":[{"name":"Dunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Il","family":"Kim","sequence":"additional","affiliation":[{"name":"Dunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk-Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Chungnam National University, Daejeon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwa-Seung","family":"Yoo","sequence":"additional","affiliation":[{"name":"Dunsan Korean Medicine Hospital of Daejeon University, Daejoen, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,6,22]]},"reference":[{"key":"bibr1-1534735416654762","first-page":"219","volume-title":"Essentials of Complementary and Alternative Medicine","volume":"1999","author":"Lao L"},{"key":"bibr2-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X01000265"},{"key":"bibr3-1534735416654762","first-page":"327","volume":"11","author":"Im ST","year":"1994","journal-title":"J Korean Acupunt Moxibust Soc"},{"key":"bibr4-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-3-284"},{"key":"bibr5-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-4833-0"},{"key":"bibr6-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-10-130"},{"key":"bibr7-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1177\/1534735413510025"},{"key":"bibr8-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(03)01247-6"},{"key":"bibr9-1534735416654762","first-page":"2425","volume":"37","author":"Holland JCB","year":"1977","journal-title":"Cancer Res"},{"key":"bibr10-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0b013e3283311d09"},{"key":"bibr11-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2005.09.001"},{"key":"bibr12-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-008-0447-8"},{"key":"bibr13-1534735416654762","volume-title":"Acupuncture and Moxibustion","author":"Korean Society of Acupuncture","year":"2012"},{"key":"bibr14-1534735416654762","volume-title":"Appropriate Use of Acupuncture and Moxibustion","author":"Daejeon Korean Medicine University 11st Alumni Group","year":"1999"},{"key":"bibr15-1534735416654762","unstructured":"Functional Assessment of Chronic Illness Therapy. FACIT. 2010. http:\/\/www.facit.org\/. Accessed May 30, 2016."},{"key":"bibr16-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.5.365"},{"key":"bibr17-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114500001719"},{"key":"bibr18-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/379291"},{"key":"bibr19-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1016\/S2095-4964(14)60024-8"},{"key":"bibr20-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1186\/ar4590"},{"key":"bibr21-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-11-124"},{"key":"bibr22-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2010.07.001"},{"key":"bibr23-1534735416654762","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i15.2174"},{"key":"bibr24-1534735416654762","first-page":"733","volume":"20","author":"Chen K","year":"2000","journal-title":"Chin J Integr Med"},{"key":"bibr25-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.04.102"},{"key":"bibr26-1534735416654762","first-page":"549","volume":"24","author":"Cao JX","year":"1997","journal-title":"Chin J Clin Oncol"},{"key":"bibr27-1534735416654762","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2011.07.005"}],"container-title":["Integrative Cancer Therapies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1534735416654762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1534735416654762","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1534735416654762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:18:26Z","timestamp":1777454306000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1534735416654762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,22]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1177\/1534735416654762"],"URL":"https:\/\/doi.org\/10.1177\/1534735416654762","relation":{},"ISSN":["1534-7354","1552-695X"],"issn-type":[{"value":"1534-7354","type":"print"},{"value":"1552-695X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,22]]}}}