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We credit her survival to a combination of (1) medicine as practiced by an excellent oncologist with whom we developed a partnership to manage the patient\u2019s health, (2) our informed exploration of the available scientific knowledge including a review of scientific research articles that go beyond conventional care, and (3) the patient\u2019s supplementation with numerous repurposed drugs and other substances reported to have antitumor properties. Alongside her conventional treatment (the medical standard of care), it seems likely that this supplementation has been a key factor in the patient\u2019s long-term survival. We also point out that the lack of follow-up magnetic resonance imaging brain scans for early detection of brain metastases poses substantial risks for patients with HER2+ metastatic breast cancer in non\u2013central nervous system locations. Thus, we suggest that research be conducted on such early detection for possible inclusion in the recommendations for the medical standard of care. Finally, medical doctors and also patients with backgrounds in biological science may wish to consider potential options and advantages of repurposed drugs and other substances reported in scientific publications when the medical standard of care has limited options for advanced cancer and other severe chronic health conditions. However, any efforts along this line by patients should be in collaboration with their medical doctors.<\/jats:p>","DOI":"10.1177\/1534735419890017","type":"journal-article","created":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T02:07:05Z","timestamp":1578362825000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Breast Cancer With Brain Metastases: Perspective From a Long-Term Survivor"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9028-3512","authenticated-orcid":false,"given":"Christopher P.","family":"Kofron","sequence":"first","affiliation":[{"name":"US Fish and Wildlife Service, Ventura, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Chapman","sequence":"additional","affiliation":[{"name":"Biology Program, California State University Channel Islands, Camarillo, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,1,6]]},"reference":[{"key":"bibr1-1534735419890017","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djv048"},{"key":"bibr2-1534735419890017","unstructured":"American Cancer Society. 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