{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:19:15Z","timestamp":1777695555750,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Zhongke Health International LLC."},{"name":"Laurance S. Rockefeller Fund"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Integr Cancer Ther"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Reishi mushroom is one of the most commonly used supplements among cancer patients. However, limited data exists on why patients choose Reishi. This study aimed to explore patients\u2019 expectations and barriers to using Reishi.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a cross-sectional survey study of a cancer population from Mainland China who reported using Reishi. Participants were recruited using a customer database from Zhongke Health International LLC. Patients\u2019 expectations and barriers to Reishi use were assessed using a modified version of the Attitudes and Beliefs Toward Complementary and Alternative Medicine (ABCAM) survey. Multivariable linear regression models were applied to examine whether socio-demographic and clinical factors, as well as Reishi usage patterns, influenced participants\u2019 attitudes toward Reishi.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 1374 participants, the most common sources of information about Reishi products were friends (49.78%) and family (36.83%). More than half (55.9%) used additional traditional Chinese herbal remedies in combination with Reishi. The most frequently cited expectations for Reishi use were boosting immunity (45% strongly agreed) and improving physical health (41% strongly agreed). 72% identified cost and insurance coverage as the primary barriers to Reishi usage. Approximately 10% considered side effects and limited research evidence as barriers. Stage IV cancer and duration of Reishi use\u2009&gt;5\u2009years were significantly associated with higher expectations and lower perceived barriers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study identified the most common expectations and barriers to Reishi use in cancer care in Mainland China. These findings can help clinicians better understand patient perspectives and integrate herbal supplements more effectively into supportive cancer care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15347354251368419","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T10:33:34Z","timestamp":1759228414000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Patients\u2019 Expectations and Barriers Toward Reishi Mushroom Use in Cancer Care: A Cross-Sectional Survey"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1006-5871","authenticated-orcid":false,"given":"Xiaotong","family":"Li","sequence":"first","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4813-0352","authenticated-orcid":false,"given":"Anna","family":"Ye","sequence":"additional","affiliation":[{"name":"New York University, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7068-4888","authenticated-orcid":false,"given":"Eunbin","family":"Kwag","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerrin","family":"Bawa","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7191-6177","authenticated-orcid":false,"given":"Lingyun","family":"Sun","sequence":"additional","affiliation":[{"name":"Xiyuan Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6432-8636","authenticated-orcid":false,"given":"Susan Qing","family":"Li","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5450-3354","authenticated-orcid":false,"given":"Yajie","family":"Zhou","sequence":"additional","affiliation":[{"name":"Zhongke Health Industry Group Corp., Ltd, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun J.","family":"Mao","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin T.","family":"Liou","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-022-03606-0"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/1534735418777117"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6874-7-4"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2010.11.018"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29173"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1201\/b10787"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0000000000000403"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2004.19.4.250"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.04.126"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039343"},{"issue":"4","key":"e_1_3_3_12_2","article-title":"Ganoderma lucidum (reishi mushroom) for cancer treatment","volume":"4","author":"Jin X","year":"2016","unstructured":"Jin X, Ruiz Beguerie J, Sze DM, Chan GC. 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