{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T15:07:30Z","timestamp":1789398450484,"version":"build-2803163510"},"reference-count":47,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Integr Cancer Ther"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Recent advancements in oncology have significantly improved cancer treatment outcomes and patient survival rates. Nonetheless, the therapeutic effects of cancer treatment often impair the patients\u2019 quality of life (QoL). The most common symptoms include fatigue, pain, sleep disturbances, depression, and anxiety. This study aims to assess the impact of a structured mind-body medicine (MBM) group intervention on these specific symptom domains in patients with cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cohort of patients with cancer engaged in an 11-week MBM program (6\u2009hours weekly, March 2016-August 2017), combining psycho-oncology, lifestyle medicine, and integrative approaches including mindfulness, nutrition counseling, and movement therapies. Participants\u2019 outcomes were evaluated for within-person (pre-post) changes using standardized questionnaires, including the Multidimensional Fatigue Index (MFI), the Perceived Stress Scale (PSS), the Pittsburgh Sleep Quality Index (PSQI), the Functional Assessment of Cancer Therapy (FACT-G), and the Hospital Anxiety and Depression Scale (HADS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Assessments from 113 participants (94.7% female, 58.9% with breast cancer) revealed significant improvements (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) across all outcome measures. Effect sizes were medium to large: fatigue (Cohen\u2019s\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.707), stress (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.708), quality of life (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.981), anxiety (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.635), depression (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.526), and sleep quality (\n                      <jats:italic toggle=\"yes\">d<\/jats:italic>\n                      \u2009=\u20090.635). Clinical significance analysis showed that 50% to 70% of participants achieved minimal clinically important differences, with FACT-G showing the highest clinical relevance (70.1% improved \u22655\u2009points). Wild bootstrap regression analysis with multiple testing correction identified baseline sleep quality as the strongest predictor: worse pre-program sleep was associated with greater improvements in depression (\u03b2\u2009=\u2009\u2212.282 [95% CI: \u22120.467 to \u22120.099],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.002) and sleep quality (\u03b2\u2009=\u2009\u2212.432 [95% CI: \u22120.620 to \u22120.244],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001), surviving Bonferroni correction.).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>MBM programs may be a valuable addition to oncology care and they could improve patients\u2019 quality of life. Incorporating these programs into standard cancer treatment protocols could provide a more holistic approach that addresses both the physical and psychological facets of cancer therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15347354251378056","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T10:00:47Z","timestamp":1760695247000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Effects of a Mind-Body Medicine Group Program for Cancer Patients: A Retrospective Cohort Study"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6770-3056","authenticated-orcid":false,"given":"Severin","family":"Schricker","sequence":"first","affiliation":[{"name":"Robert-Bosch-Hospital, Stuttgart, Germany"},{"name":"Robert Bosch Society for Medical Research, Bosch Health Campus, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Bre\u00dfmer","sequence":"additional","affiliation":[{"name":"Robert-Bosch-Hospital, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9658-1211","authenticated-orcid":false,"given":"Mark Dominik","family":"Alscher","sequence":"additional","affiliation":[{"name":"Robert-Bosch-Hospital, Stuttgart, Germany"},{"name":"Robert Bosch Society for Medical Research, Bosch Health Campus, Stuttgart, Germany"},{"name":"Robert Bosch Center for Integrative Medicine and Health, Bosch Health Campus, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8866-110X","authenticated-orcid":false,"given":"Claudia","family":"L\u00f6ffler","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, University Hospital of Wuerzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3640-8046","authenticated-orcid":false,"given":"Holger","family":"Cramer","sequence":"additional","affiliation":[{"name":"Robert Bosch Center for Integrative Medicine and Health, Bosch Health Campus, Stuttgart, Germany"},{"name":"Institute of General Practice and Interprofessional Care, University Hospital T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3728-8236","authenticated-orcid":false,"given":"Marcela","family":"Winkler","sequence":"additional","affiliation":[{"name":"Robert-Bosch-Hospital, Stuttgart, Germany"},{"name":"Robert Bosch Society for Medical Research, Bosch Health Campus, Stuttgart, Germany"},{"name":"Robert Bosch Center for Integrative Medicine and Health, Bosch Health Campus, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,17]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"International Agency for Research on Cancer. 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