{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:43:59Z","timestamp":1792809839639,"version":"4.5.0"},"reference-count":36,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"abstract":"<jats:p>\n                    Antimicrobial resistance in\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    infections has become a growing global public health threat. This study was conducted to characterize the antibiotic resistance profiles and molecular typing characteristics of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolates from diarrhea patients in Wanzhou district, Chongqing Municipality. A total of 66\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    strains were isolated 769 from clinical samples of patients with diarrhea. Of the 11 serotypes identified, the top three were\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    1,4,[5],12:i:- (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 23),\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Typhimurium (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 17), and\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Thompson (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 8). Thirteen distinct sequence types (STs) were identified among the 66\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolates, with ST34 (30.3%, 20\/66) and ST19 (25.8%, 17\/66) emerging as the predominant epidemic clones. Forty-two different antimicrobial resistance genes were identified. The aminoglycoside resistance genes aac(6\u2019)-Iaa (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 68, 98.48%), \u03b2-lactam resistance genes blaTEM-1B (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 41, 62.12%), and tetracycline resistance genes tet(A) (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 32, 48.48%) were the most predominant. The co-existence of blaCTX-M\/blaCMY-2 and qnrS was found in 11 strains.\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    from diarrhea patients in Wanzhou district showed high resistance (54.55\u201377.27%) to ampicillin, tetracycline, and streptomycin. Over half (59.10%) of the isolates exhibited multidrug resistance (MDR). A total of 4 isolates (2\n                    <jats:italic toggle=\"yes\">S.<\/jats:italic>\n                    Typhimurium and 2\n                    <jats:italic toggle=\"yes\">S.<\/jats:italic>\n                    Thompson) showed resistance to both fluoroquinolones and third-generation cephalosporins. Two isolates each of\n                    <jats:italic toggle=\"yes\">S.<\/jats:italic>\n                    Typhimurium and\n                    <jats:italic toggle=\"yes\">S.<\/jats:italic>\n                    Thompson displayed resistance to both fluoroquinolones and third-generation cephalosporins. Point mutations leading to amino acid changes were identified in gyrA and parC genes. Core genome single-nucleotide polymorphism showed phylogenetic clustering of the isolates with the same Multilocus sequence typing or serotype. Using a threshold of 15 core-genome SNPs, we speculated that six related epidemiological events existed. These findings underscore the necessity for ongoing surveillance of MDR patterns and molecular characteristics of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    , together with prudent antibiotic use, to curb further dissemination and support the development of effective prevention and control strategies.\n                  <\/jats:p>","DOI":"10.1177\/15353141251407540","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T15:49:22Z","timestamp":1767109762000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Antimicrobial Resistance Profiles and Molecular Characteristics of\n                    <i>Salmonella<\/i>\n                    Isolates from Diarrheal Patients in Wanzhou District, Chongqing, 2022\u20132024"],"prefix":"10.1177","author":[{"given":"Linghan","family":"Kong","sequence":"first","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Li","sequence":"additional","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Zhao","sequence":"additional","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansha","family":"Yuan","sequence":"additional","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Tang","sequence":"additional","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Liao","sequence":"additional","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Luo","sequence":"additional","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaomin","family":"Liu","sequence":"additional","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongqiong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Wanzhou District Center for Disease Control and Prevention, Chongqing Municipality, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Duan","sequence":"additional","affiliation":[{"name":"Chongqing Municipal Center for Disease Control and Prevention, Chongqing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,16]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/cmb.2012.0021"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-024-10890-2"},{"key":"e_1_3_4_4_1","volume-title":"Antibiotic Resistance Threats in the United States, 2019","author":"CDC","year":"2019","unstructured":"CDC. Antibiotic Resistance Threats in the United States, 2019. 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