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The role of factors such as hypercoagulability in the development of effort thrombosis is less well described. This report describes a previously healthy 21-year-old man who presented with simultaneous bilateral upper extremity DVT after hours of pushing and lifting a heavy wheelbarrow. Treatment included thrombolytic therapy followed by delayed venolysis and vein patch angioplasty. Hypercoagulable screening revealed factor V Leiden heterozygous characteristics.<\/jats:p>","DOI":"10.1177\/153857440103500506","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T23:03:41Z","timestamp":1182467021000},"page":"361-368","source":"Crossref","is-referenced-by-count":3,"title":["Simultaneous Bilateral Upper Extremity Venous Thrombosis in a Factor V Leiden Heterozygote"],"prefix":"10.1177","volume":"35","author":[{"given":"Vita V.","family":"Sullivan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth W.","family":"Wolk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Walter M.","family":"Whitehouse","sequence":"additional","affiliation":[{"name":"Department of Surgery, St. Joseph Mercy Hospital, Ann Arbor, MI"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2001,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(98)70052-7"},{"key":"atypb2","first-page":"18","volume":"17","author":"Machleder HI","year":"1991","journal-title":"Compr Ther"},{"key":"atypb3","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0272-5231(21)01097-2","volume":"16","author":"Haire WD","year":"1995","journal-title":"Clin Chest Med"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1007\/s100169900025"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(86)90225-9"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(98)70012-6"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(91)90004-A"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(93)90416-J"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(85)90129-6"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2000.107313"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1615886"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1615887"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1007\/s100169910084"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)80081-9"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(05)70004-3"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994931"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1650258"},{"key":"atypb18","first-page":"739","volume":"73","author":"Dahlback B","year":"1995","journal-title":"Functional tests and DNA-based assays, pros and cons [see comments]. 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