{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:20:46Z","timestamp":1791919246608,"version":"4.3.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2002,5]]},"abstract":"<jats:p>Present available studies suggest that heparin prevents early vessel thrombosis in the immediate postoperative (POP) period after lower extremity bypass. Long-term anticoagulation with warfarin has also been used in these patients, based on its beneficial effect in preventing long-term graft failure. To compare the effectiveness between unfractionated heparin (UH) and low-molecular-weight heparin (enoxaparin) when used as transitional therapeutic POP anticoagulant therapy, a prospective study was performed. Seventy consecutive patients undergoing lower extremity bypass were studied. The initial 35 patients were started on a drip of UH 6 hours POP. The next 35 consecutive patients were treated with enoxaparin, the first dose starting 6 hours POP. All patients underwent subsequent anticoagulation with oral warfarin. There were no statistically significant differences between the two groups with regard to demographics, percentage of above\/below the knee bypasses, type of conduit used, emergency operations, and overall complications. There was a significant difference in the length of stay (p = 0.05) in favor of the enoxaparin group, which also reflected a decreased overall cost in this group. In conclusion, POP anticoagulation with enoxaparin is as safe end effective as UH in patients undergoing lower extremity revascularization. Enoxaparin was associated with a decreased overall length of stay and hospital costs.<\/jats:p>","DOI":"10.1177\/153857440203600307","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T23:03:41Z","timestamp":1182467021000},"page":"199-205","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of the Use of Enoxaparin Versus Unfractionated Heparin in Patients Undergoing Lower Extremity Revascularization"],"prefix":"10.1177","volume":"36","author":[{"given":"Juan Carlos","family":"Paramo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Sendzischew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Sivina","sequence":"additional","affiliation":[{"name":"Department of Surgery, Mount Sinai Medical Center, Miami Beach, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2002,5,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)46697-1"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5884(96)80135-3"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92269-1"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70208-8"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V79.1.1.1"},{"key":"atypb6","first-page":"105","volume":"24","author":"Samama MM","year":"1994","journal-title":"Haemostasis"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.114.5_Supplement.666S"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(84)90007-7"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6922.159"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(91)90022-M"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1177\/000331978503600904"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(99)70109-6"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)07199-8"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1020278"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-821X(05)80459-1"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1020278"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-5096(06)60451-2"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1992.01420090120018"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800730903"},{"key":"atypb20","first-page":"453","volume":"102","author":"Kretschmer G","year":"1987","journal-title":"Surgery"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(06)80065-6"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.58.6.839"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1038\/265625a0"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-821X(05)80122-7"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1378\/chest.114.5_Supplement.489S"},{"key":"atypb26","first-page":"885","volume-title":"Current Surgical Therapy","author":"Bergan JJ","year":"1998","edition":"6"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(85)90244-0"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199505183322003"},{"key":"atypb29","doi-asserted-by":"publisher","DOI":"10.1177\/153857440003400120"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199708143370702"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603143341101"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1016\/S1078-5884(05)80129-7"}],"container-title":["Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/153857440203600307","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/153857440203600307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:44:26Z","timestamp":1777704266000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/153857440203600307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["10.1177\/153857440203600307"],"URL":"https:\/\/doi.org\/10.1177\/153857440203600307","relation":{},"ISSN":["1538-5744","1938-9116"],"issn-type":[{"value":"1538-5744","type":"print"},{"value":"1938-9116","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,5]]}}}