{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T23:34:33Z","timestamp":1788132873587,"version":"build-2803163510"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2010,3,30]],"date-time":"2010-03-30T00:00:00Z","timestamp":1269907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:p>Objective: Amputations of the lower extremity due to irreversible ischemic tissue loss are performed as distally as possible. Therefore, oftentimes wound-healing disorders develop, requiring additional surgical treatment. Methods: The amputations stumps of 10 patients with irreversible ischemic tissue loss due to arteriosclerosis were investigated within 72 hours postoperatively with indocyanine green (ICG) fluorescence. Results: For 6 of the investigated stumps, no perfusion deficit could be seen through fluorescence angiography. All stumps displayed primary healing. In the fluorescence angiography of 3 amputations, stump perfusions deficits predicted later tissue necrosis and had to be amputated again in a second operation. One amputation wound showed a small ICG perfusion deficit that represented a blood clot. Conclusion: Indocyanine green fluorescence angiography allows a perfusion analysis of amputation stumps and therefore a prediction of the expected tissue necrosis. This tool may allow reliable prediction of amputation level.<\/jats:p>","DOI":"10.1177\/1538574410362109","type":"journal-article","created":{"date-parts":[[2010,3,31]],"date-time":"2010-03-31T20:30:37Z","timestamp":1270067437000},"page":"269-273","source":"Crossref","is-referenced-by-count":28,"title":["Early Postoperative Detection of Tissue Necrosis in Amputation Stumps With Indocyanine Green Fluorescence Angiography"],"prefix":"10.1177","volume":"44","author":[{"given":"Alexander","family":"Zimmermann","sequence":"first","affiliation":[{"name":"Clinic of Vascular Surgery, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casper","family":"Roenneberg","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heiko","family":"Wendorff","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Holzbach","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery and Hand Surgery, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo E.","family":"Giunta","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery and Hand Surgery, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Henning","family":"Eckstein","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,3,30]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7389.584"},{"issue":"5","key":"atypb2","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1007\/s00104-008-1634-3","volume":"80","author":"Zimmermann A.","year":"2009","journal-title":"Chirurg."},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67704-5"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108223250806"},{"issue":"1","key":"atypb6","first-page":"33","volume":"81","author":"Dormandy J.","year":"1994","journal-title":"Hawaii Study Group. 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