{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:23:49Z","timestamp":1790414629471,"version":"4.1.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2010,5,18]],"date-time":"2010-05-18T00:00:00Z","timestamp":1274140800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:p>We aimed to determine whether remote ischemic preconditioning (IP) reduces renal damage following elective open infrarenal abdominal aortic aneurysm (AAA) repair. Sequential common iliac clamping was used to induce remote IP in randomized patients. Urinary retinol binding protein (RBP) and albumin-creatinine ratio (ACR) were measured following induction and 3, 24, and 48 hours postoperatively. In controls (n = 22), median urinary RBP increased from 112 \u00b5g\/mL (interquartile range [IQR] 96-173 \u00b5g\/mL) preoperatively to 5919 \u00b5g\/mL (IQR 283-17 788 \u00b5g\/mL) at 3 hours. Preoperative urinary RBP in preconditioned patients was 96 \u00b5g\/mL (IQR 50 to 229 \u00b5g\/mL) preoperatively, rising to 1243 \u00b5g\/mL (IQR 540 to 15400 \u00b5g\/mL) at 3 hours. Although control patients\u2019 median urinary RBP level was 5 times greater at 3 hours, there were no statistically significant differences in renal outcome indices. This trial could not confirm that remote IP reduces renal injury following elective open aneurysm surgery.<\/jats:p>","DOI":"10.1177\/1538574410370788","type":"journal-article","created":{"date-parts":[[2010,5,18]],"date-time":"2010-05-18T22:41:46Z","timestamp":1274222506000},"page":"334-340","source":"Crossref","is-referenced-by-count":84,"title":["Remote Ischemic Preconditioning for Renal Protection During Elective Open Infrarenal Abdominal Aortic Aneurysm Repair: Randomized Controlled Trial"],"prefix":"10.1177","volume":"44","author":[{"given":"Stewart R.","family":"Walsh","sequence":"first","affiliation":[{"name":"Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umar","family":"Sadat","sequence":"additional","affiliation":[{"name":"Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation 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