{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:54:03Z","timestamp":1777942443543,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2013,1,31]],"date-time":"2013-01-31T00:00:00Z","timestamp":1359590400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The aim of this study is to investigate the protective effects of methylprednisolone (MP) and pheniramine maleate (PM) on reperfusion injury of lungs developing after ischemia of the left lower extremity of rats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods:<\/jats:title>\n                    <jats:p>A total of 28 randomly selected male rats were divided into 4 groups, each consisting of 7 rats. Group 1 was the control group. Group 2 was the sham group (ischemia\/reperfusion [I\/R]). Rats in group 3 were subjected to I\/R and given PM (Ph group) and rats in group 4 were subjected to I\/R and given MP (Pn group).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Malondialdehyde levels were significantly lower in Ph group than in I\/R group ( P &lt; .05). Superoxide dismutase and glutathione peroxidase enzyme activities were found to be significantly higher in Ph group than in the I\/R group ( P &lt; .05). Histological examination demonstrated that PM had protective effects against I\/R injury. Conclusions: The PM has a protective effect against I\/R injury in rat lung.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1538574413475885","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T21:10:32Z","timestamp":1359753032000},"page":"219-224","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Assessment of Protective Effects of Pheniramine Maleate on Reperfusion Injury in Lung After Distant Organ Ischemia"],"prefix":"10.1177","volume":"47","author":[{"given":"Orhan","family":"Gokalp","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Faculty of Medicine, Izmir Katip Celebi University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail","family":"Yurekli","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Izmir Ataturk Education and Research Hospital, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muge","family":"Kiray","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alper","family":"Bagriyanik","sequence":"additional","affiliation":[{"name":"Department of Histology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ufuk","family":"Yetkin","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Izmir Ataturk Education and Research Hospital, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Banu Sarer","family":"Yurekli","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Izmir Education and Research Hospital, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serkan","family":"Gur","sequence":"additional","affiliation":[{"name":"Department of Radiology, Izmir Sifa Hospital, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Aksun","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Reanimation, Faculty of Medicine, Izmir Katip Celebi University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail Safa","family":"Satoglu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, Faculty of Medicine, Izmir Katip Celebi University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gamze","family":"Gokalp","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, DrHayri Ustundag Kad\u0131n Hastaliklari ve Dogum Hospital, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Gurbuz","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Faculty of Medicine, Izmir Katip Celebi University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,1,31]]},"reference":[{"issue":"4","key":"bibr1-1538574413475885","first-page":"308","volume":"14","author":"Uysal A","year":"2006","journal-title":"J Thorac Cardiovasc Surg"},{"key":"bibr2-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1177\/096721090201000620"},{"key":"bibr3-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2012.01.006"},{"key":"bibr4-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-007-9414-1"},{"key":"bibr5-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-005-0887-8"},{"issue":"1","key":"bibr6-1538574413475885","first-page":"45","volume":"18","author":"Yeginsu A","year":"2010","journal-title":"Turkish J Thorac Cardiovasc Surg"},{"key":"bibr7-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5978"},{"key":"bibr8-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1995.tb01133.x"},{"key":"bibr9-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2001.01195.x"},{"key":"bibr10-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-009-2011-5"},{"key":"bibr11-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-007-0627-x"},{"key":"bibr12-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1358\/mf.2007.29.1.1063495"},{"key":"bibr13-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-821X(05)80812-6"},{"key":"bibr14-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.07.029"},{"key":"bibr15-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-009-2010-6"},{"key":"bibr16-1538574413475885","first-page":"797","volume":"8","author":"Saba D","year":"2000","journal-title":"Turkish J Thorac and Cardiovasc Surg"},{"key":"bibr17-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.2000.7532"},{"key":"bibr18-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2004.07.044"},{"key":"bibr19-1538574413475885","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000225094.59283.b4"}],"container-title":["Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1538574413475885","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1538574413475885","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1538574413475885","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:55:00Z","timestamp":1777704900000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1538574413475885"}},"subtitle":["A Rat Model"],"short-title":[],"issued":{"date-parts":[[2013,1,31]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1177\/1538574413475885"],"URL":"https:\/\/doi.org\/10.1177\/1538574413475885","relation":{},"ISSN":["1538-5744","1938-9116"],"issn-type":[{"value":"1538-5744","type":"print"},{"value":"1938-9116","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,31]]}}}