{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:54:44Z","timestamp":1777942484701,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The aim of this study was to assess whether individual patients\u2019 or bypass characteristics may influence long-term results of prosthetic above-knee femoropopliteal bypasses in patients with claudication in today\u2019s endovascular era.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Seventy-one consecutivee Expanded Polytetrafluoroethylene (e-PTFE) bypasses were considered. All patients presented a debilitating claudication. Patency of grafts was achieved by Kaplan-Meier method. The association between individual patients\u2019 or graft characteristics and primary patency (PP) or secondary patency (SP) was assessed via Cox regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      An immediate technical success was achieved in all cases. No patient was lost during follow-up (8-90 months, median = 34 months). The median PP was 48 months. Occlusion occurred in 32 bypasses (45%). Eight (25%) of these were treated conservatively. Fifty-two bypasses (73%) were still patent at the end of follow-up, and 13 (25%) of these had been submitted to one or more surgical revisions. There were 2 graft infections. Of 17 (25%) patients with occluded graft at the end of follow-up, 2 (2.8%) had significant aggravation followed by limb loss. The PP was directly influenced by undetected minor distal anastomosis technical defects (hazard ratio [HR] = 5.89,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = .000002), popliteal artery size (HR = 0.62,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = 0.007), and distal anastomosis angle \u226540\u00b0 (HR = 5.55,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = .003). The SP was associated strictly to technical defects (HR = 11.08,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = .000007). Multivariable analyses confirmed the influence of technical defects (HR = 6.42,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = .000003) and anastomosis angle (HR = 1.05,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = .009) on PP and that of technical defects on SP (HR = 10.84,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = .00003). A significantly shorter SP was also observed after a previous failed endovascular treatment on the superficial femoral artery (HR = 3.73,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = .02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>An adequate arterial size, an ideal anastomotic angle, and the absence of minor, technical defects have a major role in prosthetic above-knee femoropopliteal bypass long-term outcome. A previous, failed endovascular procedure on the superficial femoral artery could markedly alter the natural history of patients with claudication because this approach seems to have a detrimental effect on long-term outcome of grafts needing surgical revisions<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1538574415627866","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T05:18:22Z","timestamp":1458105502000},"page":"72-79","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Factors Affecting Long-Term Results of Above-Knee Femoropopliteal Bypass"],"prefix":"10.1177","volume":"50","author":[{"given":"Francesco","family":"De Santis","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, Sandro Pertini Hospital, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian","family":"Pattaro","sequence":"additional","affiliation":[{"name":"Center for Biomedicine, European Academy of Bolzano (EURAC), Affiliated Institute of the University of L\u00fcbeck, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Mani","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Bressanone Hospital, Bressanone, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter Paul","family":"Pramstaller","sequence":"additional","affiliation":[{"name":"Center for Biomedicine, European Academy of Bolzano (EURAC), Affiliated Institute of the University of L\u00fcbeck, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Loreni","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Sandro Pertini Hospital, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Martini","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Bressanone Hospital, Bressanone, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,3,16]]},"reference":[{"issue":"1","key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ejvs.2006.09.024","article-title":"Fowkes FGR Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)","volume":"33","author":"Norgren L","year":"2007","unstructured":"Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FGR Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). 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