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Early recognition of IHE is important as it may mimic other diseases such as myocardial infarction, pulmonary embolism, Mallory\u2013Weiss tears, Boerhaave\u2019s syndrome, ruptured aortic aneurysms, and aortic dissection. Computed tomography is the preferred investigation method, and treatment is usually conservative. We herein present 2 cases of IHE associated with catheter-directed thrombolysis in the setting of pulmonary embolism.<\/jats:p>","DOI":"10.1177\/1538574421989863","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T23:54:55Z","timestamp":1612914895000},"page":"510-514","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Spontaneous Intramural Esophageal Hematoma Secondary to Thrombolysis in the Setting of Pulmonary Embolism"],"prefix":"10.1177","volume":"55","author":[{"given":"Nina Jalily","family":"Taghavyan","sequence":"first","affiliation":[{"name":"Cardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshide","family":"Mashayekh","sequence":"additional","affiliation":[{"name":"Rajaie Cardiovascular Medical and 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