{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:42:12Z","timestamp":1777941732747,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>Background: LDS is an autosomal dominant connective tissue disease. It is a rare multi-systemic disorder with serious vascular impact. Case report: We report a case of a 38-year-old male with Loeys-Dietz syndrome (LDS) suffering from major aortic complications. The disease initially manifested itself as a type A aortic dissection, successfully treated by open ascending aorta replacement. Ten days later, the patient developed an uncomplicated type B dissection. During follow up, the patient became symptomatic in both legs (rest pain) due to major true lumen compression. A thoracic endovascular aortic repair was performed with immediate improvement of the symptoms. During follow up, a computer tomography angiogram, showed a persistence false lumen perfusion and an aortic diameter increase. Multiple additional endovascular procedures and a final open thoracoabdominal aortic replacement were needed to exclude completely the false lumen. Conclusion: Open surgical repair is still the gold standard therapy for patients with connective tissue disease. However, with the nowadays progress, hybrid procedures could be a better option.<\/jats:p>","DOI":"10.1177\/15385744221109037","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T22:18:31Z","timestamp":1655331511000},"page":"767-771","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Complete Aortic Replacement in a Patient With Loeys-Dietz Syndrome"],"prefix":"10.1177","volume":"56","author":[{"given":"Sandrine","family":"Darigny","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, St Luc Hospital, Catholic University of Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parla","family":"Astarci","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, St Luc Hospital, Catholic University of Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5008-1879","authenticated-orcid":false,"given":"Maxime","family":"Elens","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, St Luc Hospital, Catholic University of Louvain, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,6,15]]},"reference":[{"key":"bibr1-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2014.11"},{"key":"bibr2-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-7893-1_7"},{"key":"bibr3-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1016\/S1357-2725(97)00128-3"},{"key":"bibr4-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.36056"},{"key":"bibr5-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa055695"},{"key":"bibr6-15385744221109037","doi-asserted-by":"publisher","DOI":"10.21037\/acs.2017.11.03"},{"key":"bibr7-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1016\/s0003-4975(03)00459-4"},{"key":"bibr8-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1038\/nature10145"},{"key":"bibr9-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-016-1401-8"},{"key":"bibr10-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1111\/j.1504-8191.2009.00956.x"},{"key":"bibr11-15385744221109037","doi-asserted-by":"publisher","DOI":"10.111\/j.1540-81912011.01224"},{"key":"bibr12-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.02.015"},{"key":"bibr13-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2018170120"},{"key":"bibr14-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.10.088"},{"key":"bibr15-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.10.091"},{"key":"bibr16-15385744221109037","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.08.077"},{"issue":"5","key":"bibr17-15385744221109037","first-page":"568","volume":"40","author":"Preventza O","year":"2013","journal-title":"Tex Heart Inst J"}],"container-title":["Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15385744221109037","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15385744221109037","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15385744221109037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:33:07Z","timestamp":1777703587000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15385744221109037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,15]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1177\/15385744221109037"],"URL":"https:\/\/doi.org\/10.1177\/15385744221109037","relation":{},"ISSN":["1538-5744","1938-9116"],"issn-type":[{"value":"1538-5744","type":"print"},{"value":"1938-9116","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,15]]}}}