{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:45:06Z","timestamp":1777941906715,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T00:00:00Z","timestamp":1671408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Carotid endarterectomy (CEA) performed several days after onset of symptoms has been shown to be optimal in preventing procedure-related stroke. Transcarotid artery revascularization (TCAR) is an alternative hybrid procedure to treat high-risk for CEA patients. In this investigation, our aim is to determine the effect of timing of TCAR in symptomatic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Procedures were captured prospectively at 2 independent health systems from 2016-2022 within a carotid intervention database. A retrospective analysis of this database was performed to generate cohorts by time to revascularization from onset of symptoms, with the short-interval revascularization (SIR) group defined as having a time to revascularization between 2-5\u00a0days; and long-interval revascularization (LIR) group having a time to revascularization of 6-180\u00a0days. Univariate analysis was performed comparing the cohorts at an \u03b1 of .05.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During the study period, 875 TCARs were captured, including 321 procedures performed in symptomatic patients. Of these, 84 had revascularization performed within 6\u00a0days after onset of symptoms (SIR) while 237 additional cases were completed 6 or more days after onset of symptoms (LIR). Baseline comorbidities were grossly similar between cohorts. Intraoperatively, SIR patients were less likely to develop bradycardia (4.8% vs 22.2%, P = .01) and experienced a shorter operative time (58\u00a0minutes vs 65\u00a0minutes, P = .02). Estimated blood loss, flow reversal time, radiation exposure, fluoroscopic time and contrast volume were identical between the groups. Length of stay in SIR patients was longer (1, IQR [1-3] vs 1, IQR [1-2] days, P &lt; .01). Additionally, SIR patients seemed to trend toward a higher rate of reinterventions (3.6% vs .4%, P = .06). The incidence of ipsilateral or contralateral stroke, cranial nerve palsy, myocardial infarction, hematoma, stent thrombosis and death were statistically identical between the 2 groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Like the previous results established for CEA, symptomatic patients undergoing TCAR demonstrate similar outcomes if the procedure is performed 48\u00a0hours after the neurologic event.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15385744221146678","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T08:35:56Z","timestamp":1671438956000},"page":"344-349","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Transcarotid Revascularization Timing and Early Postoperative Outcomes in Symptomatic Patients"],"prefix":"10.1177","volume":"57","author":[{"given":"Sylvestre","family":"Pineau","sequence":"first","affiliation":[{"name":"Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andres","family":"Fajardo","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naveed U.","family":"Saqib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghu L.","family":"Motaganahalli","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Keyhani","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kourosh","family":"Keyhani","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8962-9136","authenticated-orcid":false,"given":"Keisin S.","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"bibr1-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2021-018024"},{"key":"bibr2-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.032410"},{"key":"bibr3-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2020.05.034"},{"key":"bibr4-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.05.011"},{"key":"bibr5-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1177\/1526602818797986"},{"key":"bibr6-15385744221146678","volume-title":"One-Year Results of the (ROADSTER) Multicenter Trial of Transcarotid Stenting with Dynamic Flow Reversal [Internet]","author":"SCVS","year":"2018"},{"key":"bibr7-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15785-1"},{"key":"bibr8-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.05.101"},{"key":"bibr9-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"bibr10-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2020.08.148"},{"key":"bibr11-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2021.01.039"},{"key":"bibr12-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.108.173658"},{"key":"bibr13-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1177\/17085381221105178"},{"key":"bibr14-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002933"},{"key":"bibr15-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(94)90018-3"},{"issue":"8","key":"bibr16-15385744221146678","first-page":"e420","volume":"42","author":"Brott TG","year":"2011","journal-title":"Stroke"},{"key":"bibr17-15385744221146678","doi-asserted-by":"publisher","DOI":"10.1177\/23969873211012121"},{"key":"bibr18-15385744221146678","volume-title":"Stroke: National Clinical Guideline for Diagnosis and Initial Management of Acute Stroke and Transient Ischaemic Attack (TIA) [Internet]","author":"National Collaborating Centre for Chronic Conditions (UK)","year":"2008"}],"container-title":["Vascular and Endovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15385744221146678","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15385744221146678","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15385744221146678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:33:39Z","timestamp":1777703619000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15385744221146678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,19]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1177\/15385744221146678"],"URL":"https:\/\/doi.org\/10.1177\/15385744221146678","relation":{},"ISSN":["1538-5744","1938-9116"],"issn-type":[{"value":"1538-5744","type":"print"},{"value":"1938-9116","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,19]]}}}