{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T06:10:30Z","timestamp":1778911830490,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Endovascular Surg"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Carotid endarterectomy (CEA) is recommended as the standard revascularization strategy for patients with carotid stenosis, whereas carotid artery stenting (CAS) is generally reserved for high-risk surgical candidates. However, evidence comparing the safety and efficacy of both approaches in real-world practice remains heterogeneous.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 202 patients (mean age: 71.1 \u00b1 8.5\u00a0years; 152 males, 75.2%) who underwent carotid revascularization at a single center between October 2016 and April 2025. Patients with symptomatic moderate-to-severe stenosis (50-99%) and asymptomatic severe stenosis (70-99%) were included. Based on the revascularization strategy, patients were divided into CEA (n = 67) and CAS (n = 135) groups. Periprocedural (30-day), 1 and 3-year outcomes including stroke, myocardial infarction (MI), and all-cause mortality were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among patients, periprocedural stroke occurred in 4.5% of CEA patients and 2.2% of CAS patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.653), MI in 1.5% and 0%, (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.720), and all-cause mortality in 4.5% and 0.7% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.208) respectively. At 1-year follow-up, MI was significantly more frequent after CEA compared with CAS (8.6% vs 1.5%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.029), whereas stroke (8.6% vs 5.3%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.387) and all-cause mortality (10.3% vs 12.9%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.622) did not differ significantly. At 3\u00a0years, rates of stroke (12.3% vs 5.3%), MI (10.3% vs 3.8%), and all-cause mortality (22.4% vs 15.9%) were numerically higher in the CEA group, although these differences were not statistically significant. Subgroup analyses according to symptomatic status demonstrated no significant differences in 30-day, 1 or 3-year rates of stroke, MI, or all-cause mortality between the CEA and CAS groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this single-center experience, CAS achieved peri-procedural and short-term outcomes comparable to CEA, despite being performed in a more frail and comorbid patient population. These findings suggest that CAS may represent a safe and effective alternative to CEA in high-risk surgical candidates when performed by experienced operators within a multidisciplinary framework.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15385744261423761","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T18:48:44Z","timestamp":1770317324000},"page":"420-428","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Outcomes of Carotid Endarterectomy and Carotid Artery Stenting: A Single-Center Experience"],"prefix":"10.1177","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6496-7849","authenticated-orcid":false,"given":"Muhammet Cihat","family":"\u00c7elik","sequence":"first","affiliation":[{"name":"Hitit University Erol Ol\u00e7ok Education and Research Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayla Ece","family":"\u00c7elikten","sequence":"additional","affiliation":[{"name":"Hitit University Erol Ol\u00e7ok Education and Research Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah Kadir","family":"Dolu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, \u0130zmir Bak\u0131r\u00e7ay University \u00c7i\u011fli Education and Research Hospital, \u0130zmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9500-720X","authenticated-orcid":false,"given":"G\u00f6rkem","family":"Yi\u011fit","sequence":"additional","affiliation":[{"name":"Hitit University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ufuk","family":"T\u00fcrkmen","sequence":"additional","affiliation":[{"name":"Hitit University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6mer Burak","family":"\u00c7elik","sequence":"additional","affiliation":[{"name":"Hitit University Erol Ol\u00e7ok Education and Research Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ceren Ya\u011fmur","family":"Do\u011fru Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Hitit University Erol Ol\u00e7ok Education and Research Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8791-4475","authenticated-orcid":false,"given":"Macit","family":"Kal\u00e7\u0131k","sequence":"additional","affiliation":[{"name":"Hitit University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00fccahit","family":"Yetim","sequence":"additional","affiliation":[{"name":"Hitit University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00fctf\u00fc","family":"Bekar","sequence":"additional","affiliation":[{"name":"Hitit University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuf","family":"Karavelio\u011flu","sequence":"additional","affiliation":[{"name":"Hitit University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"e_1_3_4_2_2","volume-title":"The Atlas of Heart Disease and Stroke","author":"World Health Organization","year":"2021","unstructured":"World Health Organization. The Atlas of Heart Disease and Stroke. Geneva: WHO; 2021. Available from: https:\/\/www.who.int\/cardiovascular_diseases\/resources\/atlas\/en\/. 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Carotid artery stenting versus endarterectomy for treatment of carotid artery stenosis. Cochrane Database Syst Rev. 2020;2(2):CD000515. 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