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There are several ways in which weight plays a large role through a woman\u2019s reproductive life, from sex-specific conditions, such as polycystic ovarian syndrome, to changes in her fertility and pregnancy risks, to impacting her well-being during menopause. Management of weight should be patient-centered and include consideration of the patient\u2019s age, other health conditions and medications, and reproductive potential. This review highlights key considerations when treating weight in women patients, including impact on common sex-specific conditions and medications, evidence-based lifestyle counseling, and reproductive considerations of anti-obesity medications.<\/jats:p>","DOI":"10.1177\/15409996251405062","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T09:25:22Z","timestamp":1765531522000},"page":"217-224","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Weight Management Through a Woman\u2019s Life Stages: A Practical Evidence-Based Guide"],"prefix":"10.1177","volume":"35","author":[{"given":"Cecilia","family":"Scholcoff","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Yecies","sequence":"additional","affiliation":[{"name":"Department of Medicine, Stanford University School of Medicine, Stanford, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebeca","family":"Ortiz Worthington","sequence":"additional","affiliation":[{"name":"Department of Medicine, General Internal Medicine, University of Chicago Pritzker School of Medicine, Chicago, Illinois, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy H.","family":"Farkas","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"issue":"516","key":"e_1_3_3_2_2","first-page":"CS354814","article-title":"Prevalence of total, diagnosed, and undiagnosed diabetes in adults: United States, August 2021-August 2023","author":"Gwira JA","year":"2024","unstructured":"Gwira JA, , Fryar CD, , Gu Q. 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